YHIM_ECOLI
ID YHIM_ECOLI Reviewed; 350 AA.
AC P37630; P76704; Q2M7F3;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 24-NOV-2009, sequence version 2.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Inner membrane protein YhiM;
GN Name=yhiM; OrderedLocusNames=b3491, JW5944;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=8041620; DOI=10.1093/nar/22.13.2576;
RA Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.;
RT "Analysis of the Escherichia coli genome. V. DNA sequence of the region
RT from 76.0 to 81.5 minutes.";
RL Nucleic Acids Res. 22:2576-2586(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB18467.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; U00039; AAB18467.1; ALT_INIT; Genomic_DNA.
DR EMBL; U00096; AAC76516.4; -; Genomic_DNA.
DR EMBL; AP009048; BAE77803.1; -; Genomic_DNA.
DR PIR; S47711; S47711.
DR RefSeq; NP_417948.4; NC_000913.3.
DR RefSeq; WP_001028905.1; NZ_STEB01000004.1.
DR AlphaFoldDB; P37630; -.
DR BioGRID; 4261268; 138.
DR STRING; 511145.b3491; -.
DR TCDB; 9.B.245.1.2; the 10 tms uncharacterized duf2776 (duf2776) family.
DR PaxDb; P37630; -.
DR PRIDE; P37630; -.
DR EnsemblBacteria; AAC76516; AAC76516; b3491.
DR EnsemblBacteria; BAE77803; BAE77803; BAE77803.
DR GeneID; 66672627; -.
DR GeneID; 947997; -.
DR KEGG; ecj:JW5944; -.
DR KEGG; eco:b3491; -.
DR PATRIC; fig|511145.12.peg.3592; -.
DR EchoBASE; EB2140; -.
DR eggNOG; ENOG502ZA26; Bacteria.
DR HOGENOM; CLU_899389_0_0_6; -.
DR InParanoid; P37630; -.
DR OMA; GLGLVCY; -.
DR BioCyc; EcoCyc:MON0-2489; -.
DR PRO; PR:P37630; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; ISM:EcoCyc.
DR GO; GO:0071468; P:cellular response to acidic pH; IMP:EcoCyc.
DR InterPro; IPR021240; DUF2776.
DR Pfam; PF10951; DUF2776; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..350
FT /note="Inner membrane protein YhiM"
FT /id="PRO_0000169564"
FT TOPO_DOM 1..2
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 24..41
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 63..74
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 75..95
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 96..104
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 105..125
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 126..157
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 158..178
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 179..190
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 191..211
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 212..225
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 226..246
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 247..257
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 258..278
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 279..290
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 291..311
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 312..324
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 325..345
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 346..350
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 350 AA; 37657 MW; 06F32A844577C549 CRC64;
MNIYIGWLFK LIPLIMGLIC IALGGFVLES SGQSEYFVAG HVLISLAAIC LALFTTAFII
ISQLTRGVNT FYNTLFPIIG YAGSIITMIW GWALLAGNDV MADEFVAGHV IFGVGMIAAC
VSTVAASSGH FLLIPKNAAG SKSDGTPVQA YSSLIGNCLI AVPVLLTLLG FIWSITLLRS
ADITPHYVAG HVLLGLTAIC ACLIGLVATI VHQTRNTFST KEHWLWCYWV IFLGSITVLQ
GIYVLVSSDA SARLAPGIIL ICLGMICYSI FSKVWLLALV WRRTCSLANR IPMIPVFTCL
FCLFLASFLA EMAQTDMGYF IPSRVLVGLG AVCFTLFSIV SILEAGSAKK
