YHJ1_SCHPO
ID YHJ1_SCHPO Reviewed; 552 AA.
AC Q9C0V8; Q9UTV2;
DT 30-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=Uncharacterized transporter PB10D8.01;
GN ORFNames=SPBPB10D8.01;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 131-314, AND SUBCELLULAR
RP LOCATION.
RC STRAIN=ATCC 38364 / 968;
RX PubMed=10759889; DOI=10.1046/j.1365-2443.2000.00317.x;
RA Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T.,
RA Hiraoka Y.;
RT "Large-scale screening of intracellular protein localization in living
RT fission yeast cells by the use of a GFP-fusion genomic DNA library.";
RL Genes Cells 5:169-190(2000).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000269|PubMed:10759889}; Multi-
CC pass membrane protein {ECO:0000269|PubMed:10759889}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Allantoate
CC permease family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU329671; CAC36910.1; -; Genomic_DNA.
DR EMBL; AB027976; BAA87280.1; -; Genomic_DNA.
DR RefSeq; NP_595045.1; NM_001020950.2.
DR AlphaFoldDB; Q9C0V8; -.
DR SMR; Q9C0V8; -.
DR BioGRID; 277908; 6.
DR STRING; 4896.SPBPB10D8.01.1; -.
DR iPTMnet; Q9C0V8; -.
DR PaxDb; Q9C0V8; -.
DR EnsemblFungi; SPBPB10D8.01.1; SPBPB10D8.01.1:pep; SPBPB10D8.01.
DR GeneID; 2541399; -.
DR KEGG; spo:SPBPB10D8.01; -.
DR PomBase; SPBPB10D8.01; -.
DR VEuPathDB; FungiDB:SPBPB10D8.01; -.
DR eggNOG; KOG2533; Eukaryota.
DR HOGENOM; CLU_001265_0_5_1; -.
DR InParanoid; Q9C0V8; -.
DR OMA; FLHCTAY; -.
DR PhylomeDB; Q9C0V8; -.
DR PRO; PR:Q9C0V8; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0031224; C:intrinsic component of membrane; IBA:GO_Central.
DR GO; GO:0033229; F:cysteine transmembrane transporter activity; ISO:PomBase.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:1903712; P:cysteine transmembrane transport; ISO:PomBase.
DR GO; GO:0042883; P:cysteine transport; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR036259; MFS_trans_sf.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..552
FT /note="Uncharacterized transporter PB10D8.01"
FT /id="PRO_0000121376"
FT TRANSMEM 83..103
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 163..183
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 185..205
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 216..236
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 248..268
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 353..373
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 381..401
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 410..430
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 444..464
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 472..492
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..23
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 131..135
FT /note="TLFYV -> YAFLC (in Ref. 2; BAA87280)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 552 AA; 62732 MW; 37EEBD2B978C7425 CRC64;
MPQPSYADQI NVEDSSDYEK DPKEYVDKEK GYFPHVITSH ISKSSSQSHP DVSNAVLDET
FSFMQEAKDL EPLTPKQDKR LRWKLYFTVL VMLMILDMML YIDKATLSYS SILGLFEDTH
INSNQYNDIN TLFYVGFVIG QIPGHMLLQR FPVSKFVAAS TALWTIIIFL HCAAYNFSGL
MALRFFLGLV ESSLLPTMEA TIGMFFPHSE QALLQPFFYI SCYGCNIPAG FIAYGVQYAK
NTISPWKLFM IIVGGITFFL TIGLFFYYPD NTSTARFLTK KERLYTVDRV RRSNHSGIES
KTFKKYQVIE ALKDPVTWLF TFHVFCNQLS NNLAYQQNLL FTSLNVSDLN STLVGVASAG
YNCVSAIIAT YMMSVIKNQS AFHGAIWYIP SIAGGIACVA MSWDHKIGEL AAIIIASNFG
IPFIISLGWT TASCAGYTKK LTRGVMFMIG YAIANIIGPQ MWQSRDAPRY YPAWIVQIVI
AWSVSPFVLL IIRWILVRRN KKRLALLEQN KEQYEKTWIE TIDSSGNHVS GFYENSMLDL
TDQENLSFIY PL
