YHJV_ECOLI
ID YHJV_ECOLI Reviewed; 423 AA.
AC P37660; Q2M7K1;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1994, sequence version 1.
DT 03-AUG-2022, entry version 134.
DE RecName: Full=Inner membrane transport protein YhjV;
GN Name=yhjV; OrderedLocusNames=b3539, JW3508;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=8041620; DOI=10.1093/nar/22.13.2576;
RA Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.;
RT "Analysis of the Escherichia coli genome. V. DNA sequence of the region
RT from 76.0 to 81.5 minutes.";
RL Nucleic Acids Res. 22:2576-2586(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the amino acid/polyamine transporter 2 family.
CC SdaC/TdcC subfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U00039; AAB18517.1; -; Genomic_DNA.
DR EMBL; U00096; AAC76564.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE77755.1; -; Genomic_DNA.
DR PIR; S47761; S47761.
DR RefSeq; NP_417996.1; NC_000913.3.
DR RefSeq; WP_001295225.1; NZ_SSZK01000039.1.
DR AlphaFoldDB; P37660; -.
DR BioGRID; 4262531; 218.
DR STRING; 511145.b3539; -.
DR TCDB; 2.A.42.2.3; the hydroxy/aromatic amino acid permease (haaap) family.
DR PaxDb; P37660; -.
DR PRIDE; P37660; -.
DR EnsemblBacteria; AAC76564; AAC76564; b3539.
DR EnsemblBacteria; BAE77755; BAE77755; BAE77755.
DR GeneID; 58462520; -.
DR GeneID; 948057; -.
DR KEGG; ecj:JW3508; -.
DR KEGG; eco:b3539; -.
DR PATRIC; fig|511145.12.peg.3651; -.
DR EchoBASE; EB2175; -.
DR eggNOG; COG0814; Bacteria.
DR HOGENOM; CLU_052043_3_0_6; -.
DR OMA; NWVYSFL; -.
DR PhylomeDB; P37660; -.
DR BioCyc; EcoCyc:YHJV-MON; -.
DR PRO; PR:P37660; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0003333; P:amino acid transmembrane transport; IEA:InterPro.
DR GO; GO:0009314; P:response to radiation; IMP:EcoCyc.
DR InterPro; IPR018227; Amino_acid_transport_2.
DR Pfam; PF03222; Trp_Tyr_perm; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..423
FT /note="Inner membrane transport protein YhjV"
FT /id="PRO_0000093818"
FT TOPO_DOM 1..19
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 20..40
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 41..43
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 44..64
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 65..93
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 115..133
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 134..154
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 155..161
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 162..182
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 183..202
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 224..246
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 247..267
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 268..293
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 294..314
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 315..349
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 350..370
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 371
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 372..392
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 393..402
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 403..423
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 423 AA; 47258 MW; F6063B691C07B874 CRC64;
MQHNTLSKHN QKLPFTRYDF GWVLLCIGMA IGAGTVLMPV QIGLKGIWVF ITAAIIAYPA
TWVVQDIYLK TLSESDSCND YTDIISHYLG KNWGIFLGVI YFLMIIHGIF IYSLSVVFDS
ASYLKTFGLT DADLSQSLLY KVAIFAVLVA IASGGERLLF KISGPMVVVK VGIIVVFGFA
MIPHWNFANI TAFPQASVFF RDVLLTIPFC FFSAVFIQVL NPMNIAYRKR EADKVLATRL
ALRTHRISYI TLIAVILFFA FSFTFSISHE EAVSAFEQNI SALALAAQVI PGHIIHITST
VLNIFAVLTA FFGIYLGFHE AIKGIILNLL SRIIDTKKIN SRVLTLAICA FIVITLTIWV
SFRVSVLVFF QLGSPLYGIV SCLIPFFLIY KVAQLEKLRG FKAWLILLYG ILLCLSPLLK
LIE
