ID   YHK5_YEAST              Reviewed;         560 AA.
AC   P38775; D3DKZ3;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 135.
DE   RecName: Full=Putative uncharacterized protein YHR045W;
GN   OrderedLocusNames=YHR045W;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=8091229; DOI=10.1126/science.8091229;
RA   Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z.,
RA   Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T.,
RA   Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P., Louis E.J.,
RA   Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L.,
RA   St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P.,
RA   Waterston R., Wilson R., Vaudin M.;
RT   "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome
RT   VIII.";
RL   Science 265:2077-2082(1994).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; U00062; AAB68903.1; -; Genomic_DNA.
DR   EMBL; AY558098; AAS56424.1; -; Genomic_DNA.
DR   EMBL; BK006934; DAA06737.1; -; Genomic_DNA.
DR   PIR; S46734; S46734.
DR   RefSeq; NP_011911.1; NM_001179175.1.
DR   AlphaFoldDB; P38775; -.
DR   BioGRID; 36477; 168.
DR   DIP; DIP-5587N; -.
DR   IntAct; P38775; 1.
DR   MINT; P38775; -.
DR   STRING; 4932.YHR045W; -.
DR   iPTMnet; P38775; -.
DR   MaxQB; P38775; -.
DR   PaxDb; P38775; -.
DR   PRIDE; P38775; -.
DR   EnsemblFungi; YHR045W_mRNA; YHR045W; YHR045W.
DR   GeneID; 856441; -.
DR   KEGG; sce:YHR045W; -.
DR   SGD; S000001087; YHR045W.
DR   VEuPathDB; FungiDB:YHR045W; -.
DR   eggNOG; ENOG502QWA5; Eukaryota.
DR   HOGENOM; CLU_042082_0_0_1; -.
DR   InParanoid; P38775; -.
DR   OMA; TQEINVI; -.
DR   BioCyc; YEAST:G3O-31101-MON; -.
DR   PRO; PR:P38775; -.
DR   Proteomes; UP000002311; Chromosome VIII.
DR   RNAct; P38775; protein.
DR   GO; GO:0005783; C:endoplasmic reticulum; HDA:SGD.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..560
FT                   /note="Putative uncharacterized protein YHR045W"
FT                   /id="PRO_0000202893"
FT   TRANSMEM        9..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..81
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        305..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        442..462
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   560 AA;  62692 MW;  DA5D04A41758E088 CRC64;
     MNWSFLLQLV ITILLIVLGA NWLLSSFLLD FKRDLTGVAL SQQSSISSVR KENETAYYRS
     ILVPTGFPLT TGLGLSLKYK IRNGNFGDVW NAIMEVSKGK NIIKFTGREK SYSLSELNGM
     AKRIFPKLSN KNFKNIGIAN SIATVEGFTL SLASMMTSIR TGSIPHFLPA VPRQRLEDVD
     VLIIDSWKSF KMLNGSEDWY KLIVVCDDPI ESLQFDANCD VITWKELIDG FTKDTEYQYT
     PPDDNSDDKK LFAYVTSPWN GTNSFNQICL VSNIAEFIKG FPLGNELNSN EYLTISTKLA
     NSSASLQIWG KLFAVLLHGG SASFINPTTI DCESLQETTL LFTETKDVVK LIDSNSRSGL
     LNKIYLSWAT NLLSEGIFTK IARIEPHSLE KLRCVYLADN VKDAEVISTF PEKIPQLKKT
     NRRITPSTEQ LNKIRAQLGS RVVLELYCPY AIMGPVAHTN FYDYRVFGKS VDDNVVCYGT
     LSTTLEGKMV ETETNPHLNI EKKQGMLCIR GFSIGKPVES DRLEKALHLA ERFGGGEGWM
     PLVGVFGLFG QDGCLYIYNQ