YHKF_SCHPO
ID YHKF_SCHPO Reviewed; 474 AA.
AC O94432;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Uncharacterized RNA-binding protein C660.15;
GN ORFNames=SPBC660.15;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329671; CAA22535.1; -; Genomic_DNA.
DR PIR; T40627; T40627.
DR RefSeq; NP_595094.1; NM_001021001.2.
DR AlphaFoldDB; O94432; -.
DR SMR; O94432; -.
DR BioGRID; 277665; 10.
DR STRING; 4896.SPBC660.15.1; -.
DR iPTMnet; O94432; -.
DR MaxQB; O94432; -.
DR PaxDb; O94432; -.
DR PRIDE; O94432; -.
DR EnsemblFungi; SPBC660.15.1; SPBC660.15.1:pep; SPBC660.15.
DR GeneID; 2541150; -.
DR KEGG; spo:SPBC660.15; -.
DR PomBase; SPBC660.15; -.
DR VEuPathDB; FungiDB:SPBC660.15; -.
DR eggNOG; KOG4205; Eukaryota.
DR HOGENOM; CLU_012062_0_3_1; -.
DR InParanoid; O94432; -.
DR OMA; PYITIHG; -.
DR PhylomeDB; O94432; -.
DR PRO; PR:O94432; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005737; C:cytoplasm; ISO:PomBase.
DR GO; GO:0005849; C:mRNA cleavage factor complex; ISO:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:1990904; C:ribonucleoprotein complex; IBA:GO_Central.
DR GO; GO:0003730; F:mRNA 3'-UTR binding; NAS:PomBase.
DR GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR GO; GO:0006379; P:mRNA cleavage; ISO:PomBase.
DR GO; GO:0006378; P:mRNA polyadenylation; ISO:PomBase.
DR CDD; cd12577; RRM1_Hrp1p; 1.
DR CDD; cd12330; RRM2_Hrp1p; 1.
DR Gene3D; 3.30.70.330; -; 2.
DR InterPro; IPR034156; Hrp1_RRM1.
DR InterPro; IPR034155; Hrp1_RRM2.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR Pfam; PF00076; RRM_1; 2.
DR SMART; SM00360; RRM; 2.
DR SUPFAM; SSF54928; SSF54928; 2.
DR PROSITE; PS50102; RRM; 2.
PE 4: Predicted;
KW Nucleus; Reference proteome; Repeat; RNA-binding.
FT CHAIN 1..474
FT /note="Uncharacterized RNA-binding protein C660.15"
FT /id="PRO_0000310812"
FT DOMAIN 163..245
FT /note="RRM 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT DOMAIN 247..324
FT /note="RRM 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT REGION 1..163
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..474
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..26
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..41
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 42..73
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..122
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 130..152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 420..436
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 474 AA; 52818 MW; AB7C735FAACEEF51 CRC64;
MGGSDFEDDE LFKDLYGEEN EKKVESASGN QETSNVTPTK ENEGYEELEK SGEAGAERTK
ENPFREEPGA DFDRSGSDQQ YSAEAEANQE DDLNETSQQA PDPSSYDIRG QALSSATWDN
AEDGENSKND NYNENQSALT GSGAMESNED NAEETSPFNR EDGKMFIGGL NWETTDDSLR
DYFEQFGEVL DCTVMRDSTT GRSRGFGFLT FKNPKCVNEV MSKEHHLDGK IIDPKRAIPR
EEQEKTAKMF VGGVPGDCTE EEFRNFFNQF GRVLDATLMM DKDTGRPRGF GFVTYENESA
VEATMSQPYI TIHGKPVEVK RATPKASLRD SHDRHQHGYH GNANPYYAQN MNMYGGMTPA
MMAQYYRQMQ QYMEAMRNMP AAAGAVPYPQ PVMPAGMADW QQQQQQGAAY FDPSKMNQGT
GDGVPFSPSM PSGSSRGGYH GRNPGGPNRQ RYRGRRDGRG GNTGGGHSFH PYRR