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YHKF_SCHPO
ID   YHKF_SCHPO              Reviewed;         474 AA.
AC   O94432;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   03-AUG-2022, entry version 131.
DE   RecName: Full=Uncharacterized RNA-binding protein C660.15;
GN   ORFNames=SPBC660.15;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329671; CAA22535.1; -; Genomic_DNA.
DR   PIR; T40627; T40627.
DR   RefSeq; NP_595094.1; NM_001021001.2.
DR   AlphaFoldDB; O94432; -.
DR   SMR; O94432; -.
DR   BioGRID; 277665; 10.
DR   STRING; 4896.SPBC660.15.1; -.
DR   iPTMnet; O94432; -.
DR   MaxQB; O94432; -.
DR   PaxDb; O94432; -.
DR   PRIDE; O94432; -.
DR   EnsemblFungi; SPBC660.15.1; SPBC660.15.1:pep; SPBC660.15.
DR   GeneID; 2541150; -.
DR   KEGG; spo:SPBC660.15; -.
DR   PomBase; SPBC660.15; -.
DR   VEuPathDB; FungiDB:SPBC660.15; -.
DR   eggNOG; KOG4205; Eukaryota.
DR   HOGENOM; CLU_012062_0_3_1; -.
DR   InParanoid; O94432; -.
DR   OMA; PYITIHG; -.
DR   PhylomeDB; O94432; -.
DR   PRO; PR:O94432; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005737; C:cytoplasm; ISO:PomBase.
DR   GO; GO:0005849; C:mRNA cleavage factor complex; ISO:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:1990904; C:ribonucleoprotein complex; IBA:GO_Central.
DR   GO; GO:0003730; F:mRNA 3'-UTR binding; NAS:PomBase.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0006379; P:mRNA cleavage; ISO:PomBase.
DR   GO; GO:0006378; P:mRNA polyadenylation; ISO:PomBase.
DR   CDD; cd12577; RRM1_Hrp1p; 1.
DR   CDD; cd12330; RRM2_Hrp1p; 1.
DR   Gene3D; 3.30.70.330; -; 2.
DR   InterPro; IPR034156; Hrp1_RRM1.
DR   InterPro; IPR034155; Hrp1_RRM2.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF00076; RRM_1; 2.
DR   SMART; SM00360; RRM; 2.
DR   SUPFAM; SSF54928; SSF54928; 2.
DR   PROSITE; PS50102; RRM; 2.
PE   4: Predicted;
KW   Nucleus; Reference proteome; Repeat; RNA-binding.
FT   CHAIN           1..474
FT                   /note="Uncharacterized RNA-binding protein C660.15"
FT                   /id="PRO_0000310812"
FT   DOMAIN          163..245
FT                   /note="RRM 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   DOMAIN          247..324
FT                   /note="RRM 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          1..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          412..474
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..26
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        27..41
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        42..73
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        75..122
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        130..152
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        420..436
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   474 AA;  52818 MW;  AB7C735FAACEEF51 CRC64;
     MGGSDFEDDE LFKDLYGEEN EKKVESASGN QETSNVTPTK ENEGYEELEK SGEAGAERTK
     ENPFREEPGA DFDRSGSDQQ YSAEAEANQE DDLNETSQQA PDPSSYDIRG QALSSATWDN
     AEDGENSKND NYNENQSALT GSGAMESNED NAEETSPFNR EDGKMFIGGL NWETTDDSLR
     DYFEQFGEVL DCTVMRDSTT GRSRGFGFLT FKNPKCVNEV MSKEHHLDGK IIDPKRAIPR
     EEQEKTAKMF VGGVPGDCTE EEFRNFFNQF GRVLDATLMM DKDTGRPRGF GFVTYENESA
     VEATMSQPYI TIHGKPVEVK RATPKASLRD SHDRHQHGYH GNANPYYAQN MNMYGGMTPA
     MMAQYYRQMQ QYMEAMRNMP AAAGAVPYPQ PVMPAGMADW QQQQQQGAAY FDPSKMNQGT
     GDGVPFSPSM PSGSSRGGYH GRNPGGPNRQ RYRGRRDGRG GNTGGGHSFH PYRR
 
 
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