ID   YHN8_YEAST              Reviewed;         552 AA.
AC   P38799; D3DL28;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 123.
DE   RecName: Full=Uncharacterized protein YHR078W;
GN   OrderedLocusNames=YHR078W;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=8091229; DOI=10.1126/science.8091229;
RA   Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z.,
RA   Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T.,
RA   Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P., Louis E.J.,
RA   Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L.,
RA   St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P.,
RA   Waterston R., Wilson R., Vaudin M.;
RT   "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome
RT   VIII.";
RL   Science 265:2077-2082(1994).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
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DR   EMBL; U10556; AAB68887.1; -; Genomic_DNA.
DR   EMBL; BK006934; DAA06772.1; -; Genomic_DNA.
DR   PIR; S46809; S46809.
DR   RefSeq; NP_011945.1; NM_001179208.1.
DR   AlphaFoldDB; P38799; -.
DR   SMR; P38799; -.
DR   BioGRID; 36512; 91.
DR   DIP; DIP-7298N; -.
DR   IntAct; P38799; 1.
DR   STRING; 4932.YHR078W; -.
DR   iPTMnet; P38799; -.
DR   MaxQB; P38799; -.
DR   PaxDb; P38799; -.
DR   PRIDE; P38799; -.
DR   EnsemblFungi; YHR078W_mRNA; YHR078W; YHR078W.
DR   GeneID; 856477; -.
DR   KEGG; sce:YHR078W; -.
DR   SGD; S000001120; YHR078W.
DR   VEuPathDB; FungiDB:YHR078W; -.
DR   eggNOG; KOG2417; Eukaryota.
DR   HOGENOM; CLU_498921_0_0_1; -.
DR   InParanoid; P38799; -.
DR   OMA; FRFNYQH; -.
DR   BioCyc; YEAST:G3O-31125-MON; -.
DR   PRO; PR:P38799; -.
DR   Proteomes; UP000002311; Chromosome VIII.
DR   RNAct; P38799; protein.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR025969; ABA_GPCR_dom.
DR   InterPro; IPR022535; Golgi_pH-regulator_cons_dom.
DR   InterPro; IPR015672; GPHR/GTG.
DR   PANTHER; PTHR15948; PTHR15948; 1.
DR   Pfam; PF12430; ABA_GPCR; 1.
DR   Pfam; PF12537; GPHR_N; 1.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..552
FT                   /note="Uncharacterized protein YHR078W"
FT                   /id="PRO_0000202900"
FT   TRANSMEM        127..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        160..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        393..413
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        517..537
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   552 AA;  63331 MW;  8FE0AE88937E281F CRC64;
     MEALIVFIVL SVSGAFAYKC SYERLWFKVG SLFDIISTSS KKNVIPLASK MEVGSNEDVS
     SMGNFINKFY TEYSLPSHKV LQSLRVLFSL AMMTYTVTIE IILWQIKVAG MDKEVTFITT
     WVWPLTAIML SFILILFQPF FIIISLLNKF YNDKFDIDRL IIVTCIILST LIALLSYINI
     GPFQYTKNIL TRLSIGGVTV MASLSGLATV SSLYYNFLVI WHKFRNTPMS DPSFRNINNS
     NNNSKSLLWT TDAYIEEKIQ DYEHNIEQNV QILRSLEEEV GENSTFKAEL MEKIAWYQLE
     LGKLEALLQQ SPQVRTFKKA FEVGFIIYCL HKLIITFLKR IPYIIYHSLK YPDDYDYENF
     SENAASDPLA ITIANILDFS FFRFNYQHDL DSLTKQISLF LSISLFLCCL SAVNTTISYV
     VTLLPIKFQI LALFAMQNDD TANVLPEYTN NSSYKGKKRN YSQEQKGISL IKNLVVSELT
     GVYVLATTLM VRSHLPFEVS QRLKELLGGK FTVPNIVIDS WFDEVYAFAC VFTFICIRIA
     ERKLSTKKVS VE