YHOE_SCHPO
ID YHOE_SCHPO Reviewed; 350 AA.
AC O94361;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 110.
DE RecName: Full=Uncharacterized acyltransferase C428.14;
DE EC=2.3.-.-;
GN ORFNames=SPBC428.14;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000269|PubMed:16823372}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the 1-acyl-sn-glycerol-3-phosphate
CC acyltransferase family. {ECO:0000305}.
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DR EMBL; CU329671; CAA22289.1; -; Genomic_DNA.
DR PIR; T40466; T40466.
DR RefSeq; NP_595192.1; NM_001021099.2.
DR AlphaFoldDB; O94361; -.
DR BioGRID; 277363; 6.
DR IntAct; O94361; 1.
DR STRING; 4896.SPBC428.14.1; -.
DR iPTMnet; O94361; -.
DR MaxQB; O94361; -.
DR PaxDb; O94361; -.
DR EnsemblFungi; SPBC428.14.1; SPBC428.14.1:pep; SPBC428.14.
DR GeneID; 2540846; -.
DR KEGG; spo:SPBC428.14; -.
DR PomBase; SPBC428.14; -.
DR VEuPathDB; FungiDB:SPBC428.14; -.
DR eggNOG; KOG1505; Eukaryota.
DR HOGENOM; CLU_041844_3_0_1; -.
DR InParanoid; O94361; -.
DR OMA; KSVNFYW; -.
DR PhylomeDB; O94361; -.
DR Reactome; R-SPO-1482798; Acyl chain remodeling of CL.
DR Reactome; R-SPO-1482925; Acyl chain remodelling of PG.
DR Reactome; R-SPO-1483166; Synthesis of PA.
DR PRO; PR:O94361; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0012505; C:endomembrane system; IBA:GO_Central.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016411; F:acylglycerol O-acyltransferase activity; ISS:PomBase.
DR GO; GO:0016746; F:acyltransferase activity; IBA:GO_Central.
DR GO; GO:0036149; P:phosphatidylinositol acyl-chain remodeling; IBA:GO_Central.
DR GO; GO:0008654; P:phospholipid biosynthetic process; ISO:PomBase.
DR InterPro; IPR032098; Acyltransf_C.
DR InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR Pfam; PF16076; Acyltransf_C; 1.
DR Pfam; PF01553; Acyltransferase; 1.
DR SMART; SM00563; PlsC; 1.
PE 3: Inferred from homology;
KW Acyltransferase; Endoplasmic reticulum; Membrane; Reference proteome;
KW Transferase; Transmembrane; Transmembrane helix.
FT CHAIN 1..350
FT /note="Uncharacterized acyltransferase C428.14"
FT /id="PRO_0000317311"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 327..347
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 350 AA; 41354 MW; D5FBDFA896300E58 CRC64;
MTCRIAIRKY SFILCLAVGS VTIYTSEVIG TPLYFVNKEL YNKYIAFTKS FAGILFTALV
QLFSPTPVTL TYDPELRNLF YLDRNGCLET IAAERNIVIA NHQLYSDWMY VWWLSYTAKQ
HGHVYIMLKN SLKWLPVIGW GMQLFRFIFL SRKWDKDYET MSRHFKFIRN VRDSVSLILF
PEGTNLVEST YQRSRVYADK IGVKMPKHLM LPRVRGLFYS ISQLRDSMTY LYDYTFYFSD
PSPKKYAADA FSLPKLFFEG VPIKRLHIHV RRFPISEIPT EEDQFTDWLY QRWYEKDKLI
DTLLETGNFP GPKKLHTTVR LKHRLEILSL FSVLFTCIVA GLFLKLFISH
