YHS6_SCHPO
ID YHS6_SCHPO Reviewed; 498 AA.
AC O43081;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 25-MAY-2022, entry version 123.
DE RecName: Full=Uncharacterized MFS-type transporter C947.06c;
GN ORFNames=SPBC947.06c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1] {ECO:0000312|EMBL:CAA17034.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC {ECO:0000255}.
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DR EMBL; CU329671; CAA17034.1; -; Genomic_DNA.
DR PIR; T40776; T40776.
DR RefSeq; NP_595270.1; NM_001021177.2.
DR AlphaFoldDB; O43081; -.
DR BioGRID; 277789; 13.
DR STRING; 4896.SPBC947.06c.1; -.
DR PaxDb; O43081; -.
DR EnsemblFungi; SPBC947.06c.1; SPBC947.06c.1:pep; SPBC947.06c.
DR GeneID; 2541275; -.
DR KEGG; spo:SPBC947.06c; -.
DR PomBase; SPBC947.06c; -.
DR VEuPathDB; FungiDB:SPBC947.06c; -.
DR eggNOG; KOG0255; Eukaryota.
DR HOGENOM; CLU_008455_11_6_1; -.
DR InParanoid; O43081; -.
DR OMA; WGSTIFA; -.
DR PhylomeDB; O43081; -.
DR PRO; PR:O43081; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; ISO:PomBase.
DR GO; GO:0015606; F:spermidine transmembrane transporter activity; ISO:PomBase.
DR GO; GO:0000297; F:spermine transmembrane transporter activity; ISO:PomBase.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:1903711; P:spermidine transmembrane transport; IC:PomBase.
DR GO; GO:1903710; P:spermine transmembrane transport; IC:PomBase.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..498
FT /note="Uncharacterized MFS-type transporter C947.06c"
FT /id="PRO_0000343519"
FT TRANSMEM 93..113
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 153..173
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 180..200
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 214..234
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 288..308
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 327..347
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 368..388
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 393..413
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 427..449
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 461..481
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 498 AA; 55248 MW; B6341DEE97F98157 CRC64;
MKENDHLNSV SSSEIEKCDE DVEEELYSYP DSDFLVTFNG EDDPEKPLNW PVSIKLLNTA
LYGLTTFAAQ FNSTTMSPTT SHLVNAYPIG HEVAVLPTCL YILGIAFGPM IFAPFSEVNG
RKIGVLVPFF LSILFTIGTA SSDSVAAIMC TRFFAGLFAG APVVSSGGVM ADLWCPAQRG
TALIFYAFFV VSGADFGPII SSLVTEHSDT AWRWPLWTIV IIECFILTLD VFLIKETFGP
VILATKAKNL RLTTKNWGLH AAHDEYRLDF KEFVTLHLVR PFAMLATPIV FFIAMFASYV
YGILYLVLTT IPYTFGMTKN WQGTISTLPM IAMFTGVVIG GSFNIMWNQR YAKLITANGG
KPLPEQRLPL MMAVGWLMPA GIFVFAWTNS PNIHWIAPFI GISMMGAGFF VIFQGCLNYL
VDTFTKFAAS AIAANTFTRS IFAGTFPLFS EIMFKKLGVH WGGSLVGFIA LGMIPIPFIF
YMMGDKLRRK NRFIKLIT
