YHS7_YEAST
ID YHS7_YEAST Reviewed; 243 AA.
AC P38833; D3DL76;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 03-AUG-2022, entry version 142.
DE RecName: Full=Uncharacterized protein YHR127W;
GN OrderedLocusNames=YHR127W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8091229; DOI=10.1126/science.8091229;
RA Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z.,
RA Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T.,
RA Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P., Louis E.J.,
RA Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L.,
RA St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P.,
RA Waterston R., Wilson R., Vaudin M.;
RT "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome
RT VIII.";
RL Science 265:2077-2082(1994).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [4]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [5]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-96, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC STRAIN=ADR376;
RX PubMed=17330950; DOI=10.1021/pr060559j;
RA Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J.,
RA Elias J.E., Gygi S.P.;
RT "Large-scale phosphorylation analysis of alpha-factor-arrested
RT Saccharomyces cerevisiae.";
RL J. Proteome Res. 6:1190-1197(2007).
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=18407956; DOI=10.1074/mcp.m700468-mcp200;
RA Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
RT "A multidimensional chromatography technology for in-depth phosphoproteome
RT analysis.";
RL Mol. Cell. Proteomics 7:1389-1396(2008).
RN [7]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19779198; DOI=10.1126/science.1172867;
RA Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
RT "Global analysis of Cdk1 substrate phosphorylation sites provides insights
RT into evolution.";
RL Science 325:1682-1686(2009).
CC -!- MISCELLANEOUS: Present with 2140 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; U10398; AAB68406.1; -; Genomic_DNA.
DR EMBL; AY692678; AAT92697.1; -; Genomic_DNA.
DR EMBL; BK006934; DAA06820.1; -; Genomic_DNA.
DR PIR; S48971; S48971.
DR RefSeq; NP_011995.1; NM_001179257.1.
DR AlphaFoldDB; P38833; -.
DR SMR; P38833; -.
DR BioGRID; 36560; 80.
DR DIP; DIP-4719N; -.
DR IntAct; P38833; 5.
DR MINT; P38833; -.
DR STRING; 4932.YHR127W; -.
DR iPTMnet; P38833; -.
DR MaxQB; P38833; -.
DR PaxDb; P38833; -.
DR PRIDE; P38833; -.
DR EnsemblFungi; YHR127W_mRNA; YHR127W; YHR127W.
DR GeneID; 856528; -.
DR KEGG; sce:YHR127W; -.
DR SGD; S000001169; YHR127W.
DR VEuPathDB; FungiDB:YHR127W; -.
DR eggNOG; ENOG502S5CR; Eukaryota.
DR HOGENOM; CLU_073672_0_0_1; -.
DR InParanoid; P38833; -.
DR OMA; DWQSEKA; -.
DR BioCyc; YEAST:G3O-31167-MON; -.
DR PRO; PR:P38833; -.
DR Proteomes; UP000002311; Chromosome VIII.
DR RNAct; P38833; protein.
DR GO; GO:0005634; C:nucleus; IDA:SGD.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0000022; P:mitotic spindle elongation; IMP:SGD.
DR InterPro; IPR035979; RBD_domain_sf.
DR SUPFAM; SSF54928; SSF54928; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..243
FT /note="Uncharacterized protein YHR127W"
FT /id="PRO_0000202915"
FT REGION 71..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..120
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 96
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:17330950"
SQ SEQUENCE 243 AA; 27132 MW; 4EF22B6901D13934 CRC64;
MARNRTTSKK NVQSKRLIDR VVPMDKIKKV GVAKKKTVEH TKEGFSVVNG KLVSSNDVGV
LLREAQGAID KRTNVSQRNR KKGIKNNRPH KDINSSPDWG NAHRGTDWQS EKANGMNRAK
NSRNFTTNIK LQRQHFGEEI QGGSQLVIST NSDASDKLLM LFNLTLGVNQ ENLKNVLENI
SQVQIAQIRV RDLPSGSATA KVRLAYPTTQ SLEKVRKLFH GALVDGRRIQ VVIASDESSH
LSY
