YHT8_YEAST
ID YHT8_YEAST Reviewed; 114 AA.
AC P38841; D3DL87;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 03-AUG-2022, entry version 154.
DE RecName: Full=Uncharacterized protein YHR138C;
DE Flags: Precursor;
GN OrderedLocusNames=YHR138C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8091229; DOI=10.1126/science.8091229;
RA Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z.,
RA Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T.,
RA Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P., Louis E.J.,
RA Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L.,
RA St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P.,
RA Waterston R., Wilson R., Vaudin M.;
RT "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome
RT VIII.";
RL Science 265:2077-2082(1994).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=Sigma 1278B;
RA Houssaini I.I., Vissers S., Cartiaux M., Urrestarazu A.;
RL Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [5]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [6]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-41, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=18407956; DOI=10.1074/mcp.m700468-mcp200;
RA Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
RT "A multidimensional chromatography technology for in-depth phosphoproteome
RT analysis.";
RL Mol. Cell. Proteomics 7:1389-1396(2008).
CC -!- MISCELLANEOUS: Present with 319 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: Belongs to the protease inhibitor I9 family. {ECO:0000305}.
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DR EMBL; U10398; AAB68418.1; -; Genomic_DNA.
DR EMBL; Y13625; CAA73951.1; -; Genomic_DNA.
DR EMBL; AY557846; AAS56172.1; -; Genomic_DNA.
DR EMBL; BK006934; DAA06831.1; -; Genomic_DNA.
DR PIR; S48982; S48982.
DR RefSeq; NP_012006.1; NM_001179268.1.
DR AlphaFoldDB; P38841; -.
DR SMR; P38841; -.
DR BioGRID; 36571; 35.
DR DIP; DIP-4718N; -.
DR MINT; P38841; -.
DR STRING; 4932.YHR138C; -.
DR iPTMnet; P38841; -.
DR MaxQB; P38841; -.
DR PaxDb; P38841; -.
DR PRIDE; P38841; -.
DR EnsemblFungi; YHR138C_mRNA; YHR138C; YHR138C.
DR GeneID; 856540; -.
DR KEGG; sce:YHR138C; -.
DR SGD; S000001180; YHR138C.
DR VEuPathDB; FungiDB:YHR138C; -.
DR eggNOG; ENOG502S7VS; Eukaryota.
DR HOGENOM; CLU_156026_1_0_1; -.
DR InParanoid; P38841; -.
DR OMA; GSITHEY; -.
DR BioCyc; YEAST:G3O-31174-MON; -.
DR PRO; PR:P38841; -.
DR Proteomes; UP000002311; Chromosome VIII.
DR RNAct; P38841; protein.
DR GO; GO:0004866; F:endopeptidase inhibitor activity; IMP:SGD.
DR GO; GO:0042144; P:vacuole fusion, non-autophagic; IMP:SGD.
DR Gene3D; 3.30.70.80; -; 1.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome; Signal.
FT SIGNAL 1..19
FT /evidence="ECO:0000255"
FT CHAIN 20..114
FT /note="Uncharacterized protein YHR138C"
FT /id="PRO_0000026706"
FT MOD_RES 41
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:18407956"
SQ SEQUENCE 114 AA; 12753 MW; FF168CA45F2EE417 CRC64;
MKASYLVLIF ISIFSMAQAS SLSSYIVTFP KTDNMATDQN SIIEDVKKYV VDIGGKITHE
YSLIKGFTVD LPDSDQILDG LKERLSYIES EYGAKCNLEK DSEVHALNRD HLVA