YHV3_SCHPO
ID YHV3_SCHPO Reviewed; 1462 AA.
AC Q9P7R8;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Uncharacterized protein C211.03;
GN ORFNames=SPBC211.03c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-411 AND SER-420, AND
RP IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Golgi
CC apparatus membrane {ECO:0000305}; Single-pass membrane protein
CC {ECO:0000305}.
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DR EMBL; CU329671; CAB75411.1; -; Genomic_DNA.
DR PIR; T50338; T50338.
DR RefSeq; NP_596613.1; NM_001022534.2.
DR AlphaFoldDB; Q9P7R8; -.
DR SMR; Q9P7R8; -.
DR BioGRID; 277269; 2.
DR STRING; 4896.SPBC211.03c.1; -.
DR iPTMnet; Q9P7R8; -.
DR MaxQB; Q9P7R8; -.
DR PaxDb; Q9P7R8; -.
DR PRIDE; Q9P7R8; -.
DR EnsemblFungi; SPBC211.03c.1; SPBC211.03c.1:pep; SPBC211.03c.
DR GeneID; 2540746; -.
DR KEGG; spo:SPBC211.03c; -.
DR PomBase; SPBC211.03c; -.
DR VEuPathDB; FungiDB:SPBC211.03c; -.
DR eggNOG; KOG0928; Eukaryota.
DR HOGENOM; CLU_001204_3_1_1; -.
DR InParanoid; Q9P7R8; -.
DR OMA; WQHQWHT; -.
DR PhylomeDB; Q9P7R8; -.
DR Reactome; R-SPO-199992; trans-Golgi Network Vesicle Budding.
DR Reactome; R-SPO-5620916; VxPx cargo-targeting to cilium.
DR Reactome; R-SPO-6807878; COPI-mediated anterograde transport.
DR Reactome; R-SPO-6811434; COPI-dependent Golgi-to-ER retrograde traffic.
DR Reactome; R-SPO-6811438; Intra-Golgi traffic.
DR PRO; PR:Q9P7R8; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005794; C:Golgi apparatus; IDA:PomBase.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; ISO:PomBase.
DR GO; GO:0030036; P:actin cytoskeleton organization; ISO:PomBase.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; ISO:PomBase.
DR GO; GO:0043001; P:Golgi to plasma membrane protein transport; IMP:PomBase.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR GO; GO:0023052; P:signaling; NAS:PomBase.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.1000.11; -; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR InterPro; IPR032691; Sec7_N.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF12783; Sec7_N; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; SSF48371; 1.
DR SUPFAM; SSF48425; SSF48425; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Golgi apparatus; Membrane; Phosphoprotein; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..1462
FT /note="Uncharacterized protein C211.03"
FT /id="PRO_0000303920"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 541..730
FT /note="SEC7"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00189"
FT REPEAT 1102..1139
FT /note="HEAT"
FT MOD_RES 411
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 420
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 1462 AA; 165429 MW; E400D683C08CDF97 CRC64;
MEVPRASPNQ EPLCSISPSS LVINEIITVV TAIRKTTRWR NSGVASILGV STLKDEFLAD
GLESRWKTNG EKSSSIRYPL VMEFSQLKED LTNRASLNGY DSLKLLSPFL RTIKSPRMTG
YITSLCLSAI LKFFSFRIIS EESPNLALSM RNLSFAITQC RFESFDASQD EAVLLRVSRL
MEELLRGPGK AVLSDDSICE IVETGLSMCC QSRLSQVLRY SAELSMTSIL EKIFERLKYI
DVKTDSEDFW DASEEHSIKG EEFHYKKITE GDEISNEIDP FGIGSIREVF RVLVSFIDFG
KQKFSDNIKA MALRFINTAL EVSGSHISDF PSLRVLITDT LCKSLLQLIR SDHTALLTNS
LLVMTTLLQA MPGSLKLQQE LFISYLISCL HIPSTTPRER NVETSLHKVV SSLDLSEEIS
PDRATPTSFT ERKRFAFDTR NRPPEVRELI VECLGSLSRI PYFLIDLYVN YDCDPQMSDL
AIDLLKVLTR NCLVDSARYS TANVPPLCLD ALLNFIYYFH EHLQPCYNDP NNTFKDDVAK
TLIESKKRKA IIIEGAELFN ESPSDGIAFL TQHSIIKQSD NPTCIVEFFH STNRLSKRVL
GEFLTKGSNS HILNAFISAF DFKGKRIDEA LRLLLQSFRL PGESQLIERV LETFSHYYMS
ANPDSMSSKD AAFVLSYSII MLNTDQHNPN IKSQRRMTLD DFCRNVRGVN DGQDFDRNFL
SEIYKAIKEN EIIVAEEHDT ELSFLYIWSK LQQSVKITEP FKRSSSNVHD KIVFLEVWKS
IMAALIYVFS TATEDTVFYR VVNGIQQATE VAAAYELNEP VDYAIERFCQ FTALDPSSVP
GTQLNTAIKV EDRIITVSEL SVRFGRDFRA QLALLVLFWI SSKFGNIIDA SWPLLVQLTI
CLARNNLIDN SFLPGFKLFG YQWFPFPEPP LNSGKPALSK EGGLLSALSS YLSSYANDEP
PCPTDEEIQH TLCTIDCISS AKIDNFLTKL VDLKQPGLNK LLDSLLSLSN PSTSLLTDEN
TVDDNKVSSV EALSNIQSAI VADLLTSLFL GTRESLNKLE RRTQILSYLL FQIEQSGDEK
VINQLSLYIF EMFMDDDLKL SENSEDWGLF SKLCNLLNDK NIVVRNQSLS LFHQLVNKYP
FLLESWIGLQ LVQSAVNTNT ADIDDLYRLL SKIPTNLLDL PMFQVYLGCV DTLIQTIVKQ
IAQILSKQKK GASKGLPFDK SILDNHSAEL NDAFNLFLKA AVEYKVDSNE SSEHFQDTRW
KIIYDHVCKL CLSRSRSLRA ASLSCLQRIV VEQLDQPHEV SYTMALFHLV LLPTMENMIT
VLTEKPEHKI FGLAQAQMFN IICKTVLIDM NVLSAQKEML HTLWLKLMDV AIKLSSIHGS
ESMAEVMESI KNVFMILHGA GALAGPTIEV DPEIPDHLIK TWNTTWNNLF IYYPELSNDL
NINNEAEMKK ENLKNPSQTT TV
