ID   YHW5_SCHPO              Reviewed;         517 AA.
AC   Q9HGM6;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Putative transporter C543.05c;
GN   ORFNames=SPBC543.05c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000269|PubMed:16823372};
CC       Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the anion exchanger (TC 2.A.31) family.
CC       {ECO:0000305}.
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DR   EMBL; CU329671; CAC05247.1; -; Genomic_DNA.
DR   RefSeq; NP_596793.1; NM_001023813.2.
DR   AlphaFoldDB; Q9HGM6; -.
DR   SMR; Q9HGM6; -.
DR   BioGRID; 276792; 10.
DR   STRING; 4896.SPBC543.05c.1; -.
DR   MaxQB; Q9HGM6; -.
DR   PaxDb; Q9HGM6; -.
DR   EnsemblFungi; SPBC543.05c.1; SPBC543.05c.1:pep; SPBC543.05c.
DR   GeneID; 2540261; -.
DR   KEGG; spo:SPBC543.05c; -.
DR   PomBase; SPBC543.05c; -.
DR   VEuPathDB; FungiDB:SPBC543.05c; -.
DR   eggNOG; KOG1172; Eukaryota.
DR   HOGENOM; CLU_002289_7_2_1; -.
DR   InParanoid; Q9HGM6; -.
DR   OMA; AWDYRVI; -.
DR   PhylomeDB; Q9HGM6; -.
DR   PRO; PR:Q9HGM6; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0000324; C:fungal-type vacuole; HDA:PomBase.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; ISO:PomBase.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046715; F:active borate transmembrane transporter activity; ISO:PomBase.
DR   GO; GO:0080139; F:borate efflux transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0005452; F:inorganic anion exchanger activity; IEA:InterPro.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0140159; P:borate export across plasma membrane; ISO:PomBase.
DR   GO; GO:0046713; P:borate transport; IBA:GO_Central.
DR   GO; GO:0050801; P:ion homeostasis; IBA:GO_Central.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR011531; HCO3_transpt-like_TM_dom.
DR   InterPro; IPR003020; HCO3_transpt_euk.
DR   PANTHER; PTHR11453; PTHR11453; 1.
DR   Pfam; PF00955; HCO3_cotransp; 2.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix; Vacuole.
FT   CHAIN           1..517
FT                   /note="Putative transporter C543.05c"
FT                   /id="PRO_0000316208"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        93..113
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        155..175
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        186..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        217..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        269..289
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        311..331
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        377..397
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        403..423
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        449..471
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   517 AA;  58407 MW;  E999B991F959B3B8 CRC64;
     MNKKDKKFNY IFGSEIVNDV KKRLPYYKSD WIDACHYRVL PACLNIYFSN LLPELAFALD
     MFAKTNNSFG VNEVLLASVL GSVVFALLSS QPLCIVGVTG PITVFNYTVY DIMHDRGTPY
     FPFLCWICLW SMIFHFIIAI ANGVYFVKHI TKFSCEIFGL YVAFIYLEKG VQVLCDQLKY
     GLTNTFLSIT IALLFLMVGW LCDTVGKSSL FSYKVRILLL DYGLVASIIF FSGFQHIGKM
     REVSLAKLPT TKAFEPTLSR SWFIKFWKIP VGDVFLAIPF SIVLTILFYF DHNVSSVMAQ
     DPSFPLTKPA GFHWDFFLLG ITTGVSGILG IPAPNGLIPQ APMHTAALCV KRVDYDEDEI
     EKTHKEVIDR VVEQRASNFI QGLMTVGTMT GPLLLVLHQI PQCVLAGLFW VMGFSAIFGN
     GITQNVIWML SDRKVVSKNH TLNHCSSKRV VWLYTILQLI GFGATFAITQ VDKASIGFPI
     IILLLIPFRT YCMPKWFLEE DLEILDENVG IIAYQKV