YHX7_YEAST
ID YHX7_YEAST Reviewed; 453 AA.
AC P38867; D3DLC6;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 31-OCT-2006, sequence version 2.
DT 03-AUG-2022, entry version 130.
DE RecName: Full=Uncharacterized protein YHR177W;
GN OrderedLocusNames=YHR177W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=8091229; DOI=10.1126/science.8091229;
RA Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z.,
RA Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T.,
RA Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P., Louis E.J.,
RA Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L.,
RA St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P.,
RA Waterston R., Wilson R., Vaudin M.;
RT "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome
RT VIII.";
RL Science 265:2077-2082(1994).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19779198; DOI=10.1126/science.1172867;
RA Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
RT "Global analysis of Cdk1 substrate phosphorylation sites provides insights
RT into evolution.";
RL Science 325:1682-1686(2009).
CC -!- CAUTION: It is uncertain whether Met-1 or Met-2 is the initiator.
CC {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB68022.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; U00027; AAB68022.1; ALT_INIT; Genomic_DNA.
DR EMBL; BK006934; DAA06870.1; -; Genomic_DNA.
DR PIR; S48916; S48916.
DR RefSeq; NP_012047.1; NM_001179308.1.
DR PDB; 4M8B; X-ray; 2.61 A; R=6-201.
DR PDBsum; 4M8B; -.
DR AlphaFoldDB; P38867; -.
DR SMR; P38867; -.
DR BioGRID; 36610; 369.
DR DIP; DIP-2754N; -.
DR IntAct; P38867; 2.
DR MINT; P38867; -.
DR STRING; 4932.YHR177W; -.
DR iPTMnet; P38867; -.
DR PaxDb; P38867; -.
DR PRIDE; P38867; -.
DR EnsemblFungi; YHR177W_mRNA; YHR177W; YHR177W.
DR GeneID; 856582; -.
DR KEGG; sce:YHR177W; -.
DR SGD; S000001220; YHR177W.
DR VEuPathDB; FungiDB:YHR177W; -.
DR eggNOG; KOG4476; Eukaryota.
DR GeneTree; ENSGT00940000176779; -.
DR HOGENOM; CLU_605819_0_0_1; -.
DR InParanoid; P38867; -.
DR OMA; EYNIFER; -.
DR BioCyc; YEAST:G3O-31210-MON; -.
DR PRO; PR:P38867; -.
DR Proteomes; UP000002311; Chromosome VIII.
DR RNAct; P38867; protein.
DR GO; GO:0005634; C:nucleus; IC:SGD.
DR GO; GO:0003677; F:DNA binding; IDA:SGD.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; ISS:SGD.
DR InterPro; IPR018608; Gti1/Pac2.
DR PANTHER; PTHR28027; PTHR28027; 2.
DR Pfam; PF09729; Gti1_Pac2; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome.
FT CHAIN 1..453
FT /note="Uncharacterized protein YHR177W"
FT /id="PRO_0000202932"
FT REGION 183..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 428..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT STRAND 7..10
FT /evidence="ECO:0007829|PDB:4M8B"
FT HELIX 15..26
FT /evidence="ECO:0007829|PDB:4M8B"
FT HELIX 39..45
FT /evidence="ECO:0007829|PDB:4M8B"
FT STRAND 50..55
FT /evidence="ECO:0007829|PDB:4M8B"
FT HELIX 56..59
FT /evidence="ECO:0007829|PDB:4M8B"
FT STRAND 74..76
FT /evidence="ECO:0007829|PDB:4M8B"
FT STRAND 79..87
FT /evidence="ECO:0007829|PDB:4M8B"
FT STRAND 108..110
FT /evidence="ECO:0007829|PDB:4M8B"
FT STRAND 112..127
FT /evidence="ECO:0007829|PDB:4M8B"
FT STRAND 136..146
FT /evidence="ECO:0007829|PDB:4M8B"
FT HELIX 147..152
FT /evidence="ECO:0007829|PDB:4M8B"
FT HELIX 158..160
FT /evidence="ECO:0007829|PDB:4M8B"
FT HELIX 162..167
FT /evidence="ECO:0007829|PDB:4M8B"
FT HELIX 171..178
FT /evidence="ECO:0007829|PDB:4M8B"
SQ SEQUENCE 453 AA; 52048 MW; B17F12D7CCE59F60 CRC64;
MMDISPTCYG YIDDEQDLAL VFQGVFNGNL RCIERRPYDA EKVELVNPGN IFVFNEEKSG
IKRWTDGFSW SPSRISGKFL VYREYNRLGS THDLPLHNVP EYNIFERAHR KYFYTGLLKK
TFSLKFNMDP TDSTKLETFH LIAYYTEKDI HQGSLRRPSE NPFFHKFRPS QKLLDALQKV
AVGNGRSNPS KNNERGRTKA HNYKTRRSLS SSPSYCDLLS NYNNHPGNIP VRTAVQLPLT
TFNNAPREMH QQQHRQQQQY LLPIDEQNKL PLPYMQHQPQ PIGVYNPNYQ PGLRRTVSQP
MIFCNTYNTL PQQPTAAPYE RRGVSPSVIY SSNTLSPIPY QNIDPYSSRS GPECNHSKAP
IAPTMMPPVH HILVHDYRQP KPVTDSINPP NVNITTSTTN KNLDGIYILP APRMNPPAQT
QYQMIHAPDS MQHPPTFSKN NTSSNPKSHQ YSK
