ID   YHZ7_SCHPO              Reviewed;         419 AA.
AC   Q9USW3;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 111.
DE   RecName: Full=Probable glycosidase C21B10.07;
DE            EC=3.2.1.-;
GN   ORFNames=SPBC21B10.07;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 16 family. {ECO:0000305}.
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DR   EMBL; CU329671; CAB57923.1; -; Genomic_DNA.
DR   PIR; T39920; T39920.
DR   RefSeq; NP_595680.1; NM_001021575.2.
DR   AlphaFoldDB; Q9USW3; -.
DR   SMR; Q9USW3; -.
DR   BioGRID; 276863; 31.
DR   STRING; 4896.SPBC21B10.07.1; -.
DR   CAZy; GH16; Glycoside Hydrolase Family 16.
DR   MaxQB; Q9USW3; -.
DR   PaxDb; Q9USW3; -.
DR   EnsemblFungi; SPBC21B10.07.1; SPBC21B10.07.1:pep; SPBC21B10.07.
DR   GeneID; 2540333; -.
DR   KEGG; spo:SPBC21B10.07; -.
DR   PomBase; SPBC21B10.07; -.
DR   VEuPathDB; FungiDB:SPBC21B10.07; -.
DR   eggNOG; ENOG502QUM3; Eukaryota.
DR   HOGENOM; CLU_016972_1_0_1; -.
DR   InParanoid; Q9USW3; -.
DR   OMA; TEAYWNI; -.
DR   PhylomeDB; Q9USW3; -.
DR   PRO; PR:Q9USW3; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0009277; C:fungal-type cell wall; ISO:PomBase.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0071966; P:fungal-type cell wall polysaccharide metabolic process; ISO:PomBase.
DR   GO; GO:0009251; P:glucan catabolic process; IBA:GO_Central.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR000757; GH16.
DR   Pfam; PF00722; Glyco_hydro_16; 1.
DR   SUPFAM; SSF49899; SSF49899; 1.
DR   PROSITE; PS51762; GH16_2; 1.
PE   3: Inferred from homology;
KW   Glycosidase; Hydrolase; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..419
FT                   /note="Probable glycosidase C21B10.07"
FT                   /id="PRO_0000314117"
FT   TRANSMEM        88..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          122..387
FT                   /note="GH16"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01098"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          29..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        35..62
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   ACT_SITE        237
FT                   /note="Nucleophile"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        242
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   419 AA;  46508 MW;  AB1AD1E14D171FBE CRC64;
     MGIPDSTTDS RHSLSSAALS SASFENIYDP ARKNESTNDV IDNHTDTEID DHDNDHENLD
     SNNNNENNEA FNEKAAEKKL LPWYRRYFIW ILIFIVALIC SVLIGVLGGV LGHRTAVRDR
     HPSYKAKTYS LVKEYKGTTF FDGFDFMNIT DPTHGFVQYL DRNSSAKLGL ISANSSNVIM
     AADSKHNYSS GRPSIRLQST QYFEHGLFIL DLIHLPYGCG TWPAFWTLGD DWPNGGEIDI
     VEGVNVGTSN QVTLHTGDGC EMEDIKRVMT GTALQTNCWV DAPNSYNAGC GVENPSGPSY
     GEAFNKNGGG VFVLDWRSEG IRSWFFNRSE IPSDITSGSP QPAKWSEPVA DFPDTKCDID
     KMFSKQKILF DLTFCGDWAG SSVYSSAGCP GSCNDFVGNN PHNFTEAYWN IKSLAVYQY