ID   YI2A_ECOLX              Reviewed;         424 AA.
AC   P51026; Q47535;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1999, sequence version 2.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Insertion element IS2A uncharacterized 48.2 kDa protein;
OS   Escherichia coli.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Nashimoto H., Saito N.;
RL   Submitted (JUN-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transposase 8 family. {ECO:0000305}.
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DR   EMBL; D85613; BAA12836.1; -; Genomic_DNA.
DR   PIR; S78610; S78610.
DR   AlphaFoldDB; P51026; -.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0004803; F:transposase activity; IEA:InterPro.
DR   GO; GO:0015074; P:DNA integration; IEA:InterPro.
DR   GO; GO:0006313; P:transposition, DNA-mediated; IEA:InterPro.
DR   Gene3D; 3.30.420.10; -; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR025948; HTH-like_dom.
DR   InterPro; IPR001584; Integrase_cat-core.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR002514; Transposase_8.
DR   Pfam; PF13276; HTH_21; 1.
DR   Pfam; PF01527; HTH_Tnp_1; 1.
DR   Pfam; PF00665; rve; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   PROSITE; PS50994; INTEGRASE; 1.
PE   3: Inferred from homology;
KW   Transposable element.
FT   CHAIN           1..424
FT                   /note="Insertion element IS2A uncharacterized 48.2 kDa
FT                   protein"
FT                   /id="PRO_0000075492"
FT   DOMAIN          229..412
FT                   /note="Integrase catalytic"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00457"
SQ   SEQUENCE   424 AA;  48153 MW;  A791CE858D05A329 CRC64;
     MIVLILVFRL VIGEQMIDVL GPEKRRRRTT QEKIAIVQQS FEPGMTVSLV ARQHGVAASQ
     LFLWRKQYQE GSLTAVAAGE QVVPASELAA AMKQIKELQR LLGKKTMENE LLKEAVEYGR
     AKKWIAHAPL IARGWGVSLV SRCLRVSRAQ LHVILRRTDD WMDGRRSRHT DDTDVLLRIH
     HVIGELPTYG YRRVWALLRR QAELDGMPAI NAKRVYRIMR QNALLLERKP AVPPSKRAHT
     GRVAVKESNQ RWCSDGFEFC CDNGERLRVT FALDCCDREA LHWAVTTGGF NSETVQDVML
     GAVERRFGND LPSSPVEWLT DNGSCYRANE TRQFARMLGL EPKNTAVRSP ESNGIAESFV
     KTIKRDYISI MPKPDGLTAA KNLAEAFEHY NEWHPHSALG YRSPREYLRH GACNGLSDNR
     CLEI