ID   YI35_SCHPO              Reviewed;         529 AA.
AC   Q9HE16;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 116.
DE   RecName: Full=Uncharacterized transcriptional regulatory protein C1399.05c;
GN   ORFNames=SPAC1399.05c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00227,
CC       ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329670; CAC19742.1; -; Genomic_DNA.
DR   RefSeq; NP_593509.1; NM_001018943.2.
DR   AlphaFoldDB; Q9HE16; -.
DR   SMR; Q9HE16; -.
DR   BioGRID; 279003; 27.
DR   STRING; 4896.SPAC1399.05c.1; -.
DR   SwissPalm; Q9HE16; -.
DR   MaxQB; Q9HE16; -.
DR   PaxDb; Q9HE16; -.
DR   EnsemblFungi; SPAC1399.05c.1; SPAC1399.05c.1:pep; SPAC1399.05c.
DR   GeneID; 2542546; -.
DR   KEGG; spo:SPAC1399.05c; -.
DR   PomBase; SPAC1399.05c; -.
DR   VEuPathDB; FungiDB:SPAC1399.05c; -.
DR   eggNOG; ENOG502QUEK; Eukaryota.
DR   HOGENOM; CLU_021797_0_0_1; -.
DR   InParanoid; Q9HE16; -.
DR   OMA; WEYLFSQ; -.
DR   PhylomeDB; Q9HE16; -.
DR   PRO; PR:Q9HE16; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0000785; C:chromatin; IDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IMP:PomBase.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; ISM:PomBase.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR   GO; GO:0008270; F:zinc ion binding; ISM:PomBase.
DR   GO; GO:1903931; P:positive regulation of pyrimidine-containing compound salvage; IMP:PomBase.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; NAS:PomBase.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   CDD; cd00067; GAL4; 1.
DR   Gene3D; 4.10.240.10; -; 1.
DR   InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR   InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR   Pfam; PF00172; Zn_clus; 1.
DR   SMART; SM00066; GAL4; 1.
DR   SUPFAM; SSF57701; SSF57701; 1.
DR   PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR   PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation; Zinc.
FT   CHAIN           1..529
FT                   /note="Uncharacterized transcriptional regulatory protein
FT                   C1399.05c"
FT                   /id="PRO_0000310385"
FT   DNA_BIND        26..58
FT                   /note="Zn(2)-C6 fungal-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
SQ   SEQUENCE   529 AA;  60558 MW;  620D081EE47D8704 CRC64;
     MGEVERTRQS SSSLLTFKRK RALEACDSCR KQKTRCLAGS VEDENRACLR CRSLNMDCSL
     ADPNHFIRKV ENDNMDAISA NINSKLENRL KVLEKAISSI TNSPIAGQIS LKSEKDVFLQ
     GLLSMDEIEL LLEIFIERYG KRWLSVDYSA SQYMELLYTK SHLMLATACL IALRHNPSLK
     ARIYTDVLNI VDRLISEELL TTSPSLQFFE AVSMLTLYRP LRLSQKQDLW LLSGFALQHR
     TLSSTKGWFN GFAGSSATLT YLDIVPARTW NHLCHGHLVM CMGYRRHAML DENTFDDCRN
     ILTNTKANEF DGNILGMLSV YSMLYRMLRS PTLDLDYAIF QLEEWRKEWC HLWEQPEPQY
     SRIAYFYSYN VVYEASIQTA TDGNDFANIP RYVSMVQSYA LKTIDAIFEL SAYDMSRCSD
     HVLFHAGFAS ASLLRLIYAA KTKEVDTSIV QPKVLNDLVT KIWKWLLVIS VDQYHLATKF
     ANYLKEYQKT VNEGTAESTW FKGPLRPVSS TTLQALKPYN LGVATVERG