ID   YI41_SCHPO              Reviewed;         269 AA.
AC   P0CS86; Q9P3V9;
DT   18-APR-2012, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2012, sequence version 1.
DT   25-MAY-2022, entry version 47.
DE   RecName: Full=UPF0494 membrane protein C1348.01;
GN   ORFNames=SPBC1348.01;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000269|PubMed:16823372};
CC       Multi-pass membrane protein {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the UPF0494 family. {ECO:0000305}.
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DR   EMBL; CU329671; CAB94268.1; -; Genomic_DNA.
DR   RefSeq; NP_592763.1; NM_001020926.2.
DR   RefSeq; XP_001713154.1; XM_001713102.2.
DR   AlphaFoldDB; P0CS86; -.
DR   SMR; P0CS86; -.
DR   BioGRID; 277923; 24.
DR   BioGRID; 279523; 44.
DR   STRING; 4896.SPBC1348.01.1; -.
DR   PaxDb; P0CS86; -.
DR   EnsemblFungi; SPBC1348.01.1; SPBC1348.01.1:pep; SPBC1348.01.
DR   EnsemblFungi; SPBCPT2R1.01c.1; SPBCPT2R1.01c.1:pep; SPBCPT2R1.01c.
DR   GeneID; 2543090; -.
DR   KEGG; spo:SPBC1348.01; -.
DR   PomBase; SPBC1348.01; -.
DR   VEuPathDB; FungiDB:SPBC1348.01; -.
DR   VEuPathDB; FungiDB:SPBCPT2R1.01c; -.
DR   HOGENOM; CLU_097271_0_0_1; -.
DR   PhylomeDB; P0CS86; -.
DR   PRO; PR:P0CS86; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0000324; C:fungal-type vacuole; HDA:PomBase.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR009340; DUF999.
DR   Pfam; PF06198; DUF999; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix; Vacuole.
FT   CHAIN           1..269
FT                   /note="UPF0494 membrane protein C1348.01"
FT                   /id="PRO_0000306279"
FT   TRANSMEM        107..127
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        144..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        177..197
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        201..221
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   269 AA;  30580 MW;  E6DFDE8230B2A98D CRC64;
     MSNPESLKKQ VEPPGYNELF MVEDVCNVDL EQGLDLCKPE KVNKQSQRSR QSRQSLFTNT
     IKPQKDKMNI KTNKIKEFLN DLFTEFSKFH NSYYPDGRIS TRSNFRWPLL IIWSIIIVFA
     VDKKFEVQKF LSIWINENRF YSEIWVPIAI YVCLLVLMLL SLIFFAEFAV LALRVTGVII
     AVLGMIIAVL GMIIAALGAT ITGLLYFGHW ALYKLVILSL GFKIVTPGDV CVSNTLPTHN
     GETALHSETT VGSDIEQIEL QNMPTPVKK