ID   YI78_SCHPO              Reviewed;         236 AA.
AC   P0CU00; Q9P324;
DT   07-SEP-2016, integrated into UniProtKB/Swiss-Prot.
DT   07-SEP-2016, sequence version 1.
DT   03-AUG-2022, entry version 21.
DE   RecName: Full=Uncharacterized oxidoreductase SPAC977.08;
DE            EC=1.-.-.-;
GN   ORFNames=SPAC977.08;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR)
CC       family. {ECO:0000305}.
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DR   EMBL; CU329670; CAB69630.1; -; Genomic_DNA.
DR   PIR; T50280; T50280.
DR   RefSeq; NP_592771.1; NM_001020934.1.
DR   RefSeq; NP_592780.1; NM_001018180.2.
DR   AlphaFoldDB; P0CU00; -.
DR   SMR; P0CU00; -.
DR   EnsemblFungi; SPAC977.08.1; SPAC977.08.1:pep; SPAC977.08.
DR   EnsemblFungi; SPBC1348.09.1; SPBC1348.09.1:pep; SPBC1348.09.
DR   GeneID; 2541718; -.
DR   GeneID; 2543330; -.
DR   KEGG; spo:SPAC977.08; -.
DR   KEGG; spo:SPBC1348.09; -.
DR   PomBase; SPAC977.08; -.
DR   VEuPathDB; FungiDB:SPAC977.08; -.
DR   VEuPathDB; FungiDB:SPBC1348.09; -.
DR   OMA; EICDIIF; -.
DR   PhylomeDB; P0CU00; -.
DR   PRO; PR:P0CU00; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0000140; F:acylglycerone-phosphate reductase activity; ISO:PomBase.
DR   GO; GO:0006654; P:phosphatidic acid biosynthetic process; ISO:PomBase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   Pfam; PF00106; adh_short; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   PRINTS; PR00080; SDRFAMILY.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Nucleus; Oxidoreductase; Reference proteome.
FT   CHAIN           1..236
FT                   /note="Uncharacterized oxidoreductase SPAC977.08"
FT                   /id="PRO_0000437227"
FT   ACT_SITE        114
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
FT   BINDING         101
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   236 AA;  26452 MW;  C0E2AD3C9674B3C8 CRC64;
     MREPKNAKVL SRLENVLVTQ LDVNNFSSIK KSVEKAISHF GRIDVLLNNA GYSVYSPLES
     TTEEQIHNIF NTNVFGALEV IKAITPIFRS QHNGMIINVS SIGGKMTFPL GCLYYGTKYA
     IEGISEALTW EMQSIGVKVK IIEPGFTATE FRVEEGAGKH YAEYDNLKQK LYEDLLPKLK
     TATPPQKIAE VILQAATDES DELRYPTGDY VVEWMALRSK VDDATFLATH RKQMGL