ID   YIA1_YEAST              Reviewed;         513 AA.
AC   P40560; D6VVT0;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 166.
DE   RecName: Full=Ankyrin repeat-containing protein YIL001W;
GN   OrderedLocusNames=YIL001W; ORFNames=YIA1W;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=7762303; DOI=10.1002/yea.320110109;
RA   Voss H., Tamames J., Teodoru C., Valencia A., Sensen C., Wiemann S.,
RA   Schwager C., Zimmermann J., Sander C., Ansorge W.;
RT   "Nucleotide sequence and analysis of the centromeric region of yeast
RT   chromosome IX.";
RL   Yeast 11:61-78(1995).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169870;
RA   Churcher C.M., Bowman S., Badcock K., Bankier A.T., Brown D.,
RA   Chillingworth T., Connor R., Devlin K., Gentles S., Hamlin N., Harris D.E.,
RA   Horsnell T., Hunt S., Jagels K., Jones M., Lye G., Moule S., Odell C.,
RA   Pearson D., Rajandream M.A., Rice P., Rowley N., Skelton J., Smith V.,
RA   Walsh S.V., Whitehead S., Barrell B.G.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome IX.";
RL   Nature 387:84-87(1997).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [4]
RP   LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX   PubMed=14562106; DOI=10.1038/nature02046;
RA   Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA   O'Shea E.K., Weissman J.S.;
RT   "Global analysis of protein expression in yeast.";
RL   Nature 425:737-741(2003).
CC   -!- INTERACTION:
CC       P40560; Q08273: HRT1; NbExp=4; IntAct=EBI-24911, EBI-31686;
CC   -!- MISCELLANEOUS: Present with 195 molecules/cell in log phase SD medium.
CC       {ECO:0000269|PubMed:14562106}.
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DR   EMBL; X79743; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; Z38062; CAA86202.1; -; Genomic_DNA.
DR   EMBL; BK006942; DAA08546.1; -; Genomic_DNA.
DR   PIR; S48434; S48434.
DR   RefSeq; NP_012265.3; NM_001179351.3.
DR   AlphaFoldDB; P40560; -.
DR   SMR; P40560; -.
DR   BioGRID; 34991; 22.
DR   DIP; DIP-1375N; -.
DR   IntAct; P40560; 2.
DR   MINT; P40560; -.
DR   STRING; 4932.YIL001W; -.
DR   iPTMnet; P40560; -.
DR   MaxQB; P40560; -.
DR   PaxDb; P40560; -.
DR   PRIDE; P40560; -.
DR   EnsemblFungi; YIL001W_mRNA; YIL001W; YIL001W.
DR   GeneID; 854816; -.
DR   KEGG; sce:YIL001W; -.
DR   SGD; S000001263; YIL001W.
DR   VEuPathDB; FungiDB:YIL001W; -.
DR   eggNOG; KOG0511; Eukaryota.
DR   HOGENOM; CLU_022885_2_0_1; -.
DR   InParanoid; P40560; -.
DR   OMA; LQYDYSK; -.
DR   BioCyc; YEAST:G3O-31281-MON; -.
DR   PRO; PR:P40560; -.
DR   Proteomes; UP000002311; Chromosome IX.
DR   RNAct; P40560; protein.
DR   GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR   GO; GO:0000151; C:ubiquitin ligase complex; IBA:GO_Central.
DR   Gene3D; 1.25.40.20; -; 1.
DR   Gene3D; 3.30.710.10; -; 2.
DR   InterPro; IPR044515; ABTB1.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   PANTHER; PTHR46231; PTHR46231; 1.
DR   Pfam; PF13637; Ank_4; 1.
DR   Pfam; PF00651; BTB; 2.
DR   SMART; SM00248; ANK; 2.
DR   SMART; SM00225; BTB; 2.
DR   SUPFAM; SSF48403; SSF48403; 1.
DR   SUPFAM; SSF54695; SSF54695; 2.
DR   PROSITE; PS50297; ANK_REP_REGION; 1.
DR   PROSITE; PS50088; ANK_REPEAT; 1.
DR   PROSITE; PS50097; BTB; 2.
PE   1: Evidence at protein level;
KW   ANK repeat; Reference proteome; Repeat.
FT   CHAIN           1..513
FT                   /note="Ankyrin repeat-containing protein YIL001W"
FT                   /id="PRO_0000067246"
FT   REPEAT          8..37
FT                   /note="ANK 1"
FT   REPEAT          41..70
FT                   /note="ANK 2"
FT   DOMAIN          122..179
FT                   /note="BTB 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT   DOMAIN          274..360
FT                   /note="BTB 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
SQ   SEQUENCE   513 AA;  59732 MW;  3E777D8A6EE7947E CRC64;
     MADKLMDKNF EELCYSCRTG DMDNVDRLIS TGVNVNSVDK FDNSPLFLAS LCGHEAVVKL
     LLQRGAVCDR DRYEGARCIY GALTDTIRDT LLSYDISKAV DVKQPFATHI SSMYNDEGFL
     KRDITFRVSN GKLFTAHKFL LCARSEILAE KMVNEWAKHE IVSLEVRPDI FDIFLKFLYL
     IPILHQIEPG QYEELIELSS KFDIELLPEF LDKARHTADP TEKSRLMSDY QYKFTEVARS
     QLLIFVNNCI FRSTVDLANS ERRVFSLMNC PAYPDVQLMV KNRNGAIRIY PCHLAVLSRA
     EYFKVMFTNN FKEKVTYIKA KHVTGKYNSI IPQLTLPNCE FEVAEIILRY LYADNTDIPW
     MYAVDVLLLA DILLEDRLKT IASTIITQSK EFIQQYNVFD VLYLSWEIGV ERLEQFAAKF
     IAIHLQELYK DPEIKRAIML SSQRISLRQE TDTIELVDDI RYYLLRKYSF EPDDVELFEN
     QDDLEYLKQV GYLEYRKDMG MLDNILADLE LDV