ID   YIAA_ECOLI              Reviewed;         145 AA.
AC   P0ADJ8; P11287; P76715; Q2M7M5;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Inner membrane protein YiaA;
GN   Name=yiaA; OrderedLocusNames=b3562, JW3534;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12 / MM294 / ATCC 33625 / DSM 5208;
RX   PubMed=6320721; DOI=10.1128/aem.47.1.15-21.1984;
RA   Lawlis V.B., Dennis M.S., Chen E.Y., Smith D.H., Henner D.J.;
RT   "Cloning and sequencing of the xylose isomerase and xylulose kinase genes
RT   of Escherichia coli.";
RL   Appl. Environ. Microbiol. 47:15-21(1984).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=8041620; DOI=10.1093/nar/22.13.2576;
RA   Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.;
RT   "Analysis of the Escherichia coli genome. V. DNA sequence of the region
RT   from 76.0 to 81.5 minutes.";
RL   Nucleic Acids Res. 22:2576-2586(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   TOPOLOGY [LARGE SCALE ANALYSIS].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=15919996; DOI=10.1126/science.1109730;
RA   Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT   "Global topology analysis of the Escherichia coli inner membrane
RT   proteome.";
RL   Science 308:1321-1323(2005).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB18539.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; K01996; AAA24770.1; -; Genomic_DNA.
DR   EMBL; X04691; CAB46441.1; -; Genomic_DNA.
DR   EMBL; U00039; AAB18539.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAC76586.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77731.1; -; Genomic_DNA.
DR   RefSeq; NP_418019.4; NC_000913.3.
DR   RefSeq; WP_001296808.1; NZ_STEB01000018.1.
DR   AlphaFoldDB; P0ADJ8; -.
DR   BioGRID; 4261726; 8.
DR   STRING; 511145.b3562; -.
DR   TCDB; 9.B.44.1.1; the yiaa-yiab (yiaab) family.
DR   PaxDb; P0ADJ8; -.
DR   PRIDE; P0ADJ8; -.
DR   EnsemblBacteria; AAC76586; AAC76586; b3562.
DR   EnsemblBacteria; BAE77731; BAE77731; BAE77731.
DR   GeneID; 66672549; -.
DR   GeneID; 948078; -.
DR   KEGG; ecj:JW3534; -.
DR   KEGG; eco:b3562; -.
DR   PATRIC; fig|1411691.4.peg.3150; -.
DR   EchoBASE; EB1172; -.
DR   eggNOG; COG4682; Bacteria.
DR   HOGENOM; CLU_123353_0_0_6; -.
DR   OMA; GFYAFAF; -.
DR   PhylomeDB; P0ADJ8; -.
DR   BioCyc; EcoCyc:EG11186-MON; -.
DR   PRO; PR:P0ADJ8; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IEP:EcoliWiki.
DR   InterPro; IPR038972; YiaA-like.
DR   InterPro; IPR008024; YiaAB.
DR   PANTHER; PTHR37290; PTHR37290; 1.
DR   Pfam; PF05360; YiaAB; 2.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..145
FT                   /note="Inner membrane protein YiaA"
FT                   /id="PRO_0000169587"
FT   TOPO_DOM        1..12
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        13..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        33..41
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        42..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        60..71
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        95..98
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        99..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        122..145
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   145 AA;  16123 MW;  579C7073D3AEC5D5 CRC64;
     MDNKISTYSP AFSIVSWIAL VGGIVTYLLG LWNAEMQLNE KGYYFAVLVL GLFSAASYQK
     TVRDKYEGIP TTSIYYMTCL TVFIISVALL MVGLWNATLL LSEKGFYGLA FFLSLFGAVA
     VQKNIRDAGI NPPKETQVTQ EEYSE