YIAO_ECOLI
ID YIAO_ECOLI Reviewed; 328 AA.
AC P37676; Q2M7P2;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1994, sequence version 1.
DT 03-AUG-2022, entry version 139.
DE RecName: Full=2,3-diketo-L-gulonate-binding periplasmic protein YiaO;
DE Short=2,3-DKG-binding protein;
DE AltName: Full=Extracytoplasmic solute receptor protein YiaO;
DE Flags: Precursor;
GN Name=yiaO; OrderedLocusNames=b3579, JW3551;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=8041620; DOI=10.1093/nar/22.13.2576;
RA Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.;
RT "Analysis of the Escherichia coli genome. V. DNA sequence of the region
RT from 76.0 to 81.5 minutes.";
RL Nucleic Acids Res. 22:2576-2586(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP PRELIMINARY FUNCTION.
RC STRAIN=K12;
RX PubMed=14668138; DOI=10.1080/09687680310001607369;
RA Plantinga T.H., van der Does C., Badia J., Aguilar J., Konings W.N.,
RA Driessen A.J.M.;
RT "Functional characterization of the Escherichia coli K-12 yiaMNO transport
RT protein genes.";
RL Mol. Membr. Biol. 21:51-57(2004).
RN [5]
RP DELETION STUDIES.
RC STRAIN=K12;
RX PubMed=15870475; DOI=10.1099/mic.0.27851-0;
RA Plantinga T.H., van der Does C., Tomkiewicz D., van Keulen G.,
RA Konings W.N., Driessen A.J.M.;
RT "Deletion of the yiaMNO transporter genes affects the growth
RT characteristics of Escherichia coli K-12.";
RL Microbiology 151:1683-1689(2005).
RN [6]
RP FUNCTION, SUBCELLULAR LOCATION, AND MASS SPECTROMETRY.
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16385129; DOI=10.1099/mic.0.28334-0;
RA Thomas G.H., Southworth T., Leon-Kempis M.R., Leech A., Kelly D.J.;
RT "Novel ligands for the extracellular solute receptors of two bacterial TRAP
RT transporters.";
RL Microbiology 152:187-198(2006).
CC -!- FUNCTION: Part of the tripartite ATP-independent periplasmic (TRAP)
CC transport system YiaMNO involved in the uptake of 2,3-diketo-L-
CC gulonate. This protein specifically binds 2,3-diketo-L-gulonate. Is not
CC able to bind either L-ascorbate or dehydroascorbate.
CC {ECO:0000269|PubMed:16385129}.
CC -!- SUBUNIT: The complex comprises the extracytoplasmic solute receptor
CC protein YiaO, and the two transmembrane proteins YiaM and YiaN.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000269|PubMed:16385129}.
CC -!- MASS SPECTROMETRY: Mass=33468.8; Mass_error=2; Method=Electrospray;
CC Evidence={ECO:0000269|PubMed:16385129};
CC -!- SIMILARITY: Belongs to the bacterial solute-binding protein 7 family.
CC {ECO:0000305}.
CC -!- CAUTION: Was originally proposed to be a subunit from an L-xylulose
CC uptake system, but PubMed:16385129 shows that YiaO does not bind L- or
CC D-xylulose. {ECO:0000305|PubMed:14668138}.
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DR EMBL; U00039; AAB18556.1; -; Genomic_DNA.
DR EMBL; U00096; AAC76603.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE77714.1; -; Genomic_DNA.
DR PIR; S47800; S47800.
DR RefSeq; NP_418036.1; NC_000913.3.
DR RefSeq; WP_000776887.1; NZ_SSZK01000041.1.
DR AlphaFoldDB; P37676; -.
DR SMR; P37676; -.
DR BioGRID; 4262009; 5.
DR ComplexPortal; CPX-4681; YiaMNO tripartite ATP-independent periplasmic transporter complex.
DR STRING; 511145.b3579; -.
DR TCDB; 2.A.56.1.2; the tripartite atp-independent periplasmic transporter (trap-t) family.
DR jPOST; P37676; -.
DR PaxDb; P37676; -.
DR PRIDE; P37676; -.
DR EnsemblBacteria; AAC76603; AAC76603; b3579.
DR EnsemblBacteria; BAE77714; BAE77714; BAE77714.
DR GeneID; 948091; -.
DR KEGG; ecj:JW3551; -.
DR KEGG; eco:b3579; -.
DR PATRIC; fig|1411691.4.peg.3133; -.
DR EchoBASE; EB2191; -.
DR eggNOG; COG1638; Bacteria.
DR HOGENOM; CLU_036176_1_1_6; -.
DR InParanoid; P37676; -.
DR OMA; FRIMPSE; -.
DR PhylomeDB; P37676; -.
DR BioCyc; EcoCyc:EG12283-MON; -.
DR BioCyc; MetaCyc:EG12283-MON; -.
DR PRO; PR:P37676; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016020; C:membrane; IC:ComplexPortal.
DR GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR GO; GO:0031317; C:tripartite ATP-independent periplasmic transporter complex; IC:ComplexPortal.
DR GO; GO:0030246; F:carbohydrate binding; IDA:EcoCyc.
DR GO; GO:0034219; P:carbohydrate transmembrane transport; IC:ComplexPortal.
DR GO; GO:0008643; P:carbohydrate transport; IDA:EcoCyc.
DR GO; GO:0006974; P:cellular response to DNA damage stimulus; IEP:EcoliWiki.
DR GO; GO:1902075; P:cellular response to salt; IC:ComplexPortal.
DR GO; GO:1900190; P:regulation of single-species biofilm formation; IC:ComplexPortal.
DR Gene3D; 3.40.190.170; -; 1.
DR InterPro; IPR018389; DctP_fam.
DR InterPro; IPR004682; TRAP_DctP.
DR InterPro; IPR038404; TRAP_DctP_sf.
DR PANTHER; PTHR33376; PTHR33376; 1.
DR Pfam; PF03480; DctP; 1.
DR PIRSF; PIRSF006470; DctB; 1.
DR TIGRFAMs; TIGR00787; dctP; 1.
PE 1: Evidence at protein level;
KW Periplasm; Reference proteome; Signal; Transport.
FT SIGNAL 1..24
FT /evidence="ECO:0000305"
FT CHAIN 25..328
FT /note="2,3-diketo-L-gulonate-binding periplasmic protein
FT YiaO"
FT /id="PRO_0000031813"
SQ SEQUENCE 328 AA; 35970 MW; EB44605FE87BCFF8 CRC64;
MKLRSVTYAL FIAGLAAFST SSLAAQSLRF GYETSQTDSQ HIAAKKFNDL LQERTKGELK
LKLFPDSTLG NAQAMISGVR GGTIDMEMSG SNNFAGLSPV MNLLDVPFLF RDTAHAHKTL
DGKVGDDLKA SLEGKGLKVL AYWENGWRDV TNSRAPVKTP ADLKGLKIRT NNSPMNIAAF
KVFGANPIPM PFAEVYTGLE TRTIDAQEHP INVVWSAKFF EVQKFLSLTH HAYSPLLVVI
NKAKFDGLSP EFQQALVSSA QEAGNYQRKL VAEDQQKIID GMKEAGVEVI TDLDRKAFSD
ALGNQVRDMF VKDVPQGADL LKAVDEVQ
