ID   YIAU_ECOLI              Reviewed;         324 AA.
AC   P37682; Q2M7P8;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   03-AUG-2022, entry version 140.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator YiaU;
GN   Name=yiaU; OrderedLocusNames=b3585, JW3557;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=8041620; DOI=10.1093/nar/22.13.2576;
RA   Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.;
RT   "Analysis of the Escherichia coli genome. V. DNA sequence of the region
RT   from 76.0 to 81.5 minutes.";
RL   Nucleic Acids Res. 22:2576-2586(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000305}.
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DR   EMBL; U00039; AAB18562.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC76609.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77708.1; -; Genomic_DNA.
DR   PIR; S47806; S47806.
DR   RefSeq; NP_418042.1; NC_000913.3.
DR   RefSeq; WP_000164036.1; NZ_SSZK01000041.1.
DR   AlphaFoldDB; P37682; -.
DR   SMR; P37682; -.
DR   BioGRID; 4262551; 4.
DR   DIP; DIP-12411N; -.
DR   STRING; 511145.b3585; -.
DR   PaxDb; P37682; -.
DR   PRIDE; P37682; -.
DR   DNASU; 948107; -.
DR   EnsemblBacteria; AAC76609; AAC76609; b3585.
DR   EnsemblBacteria; BAE77708; BAE77708; BAE77708.
DR   GeneID; 66672523; -.
DR   GeneID; 948107; -.
DR   KEGG; ecj:JW3557; -.
DR   KEGG; eco:b3585; -.
DR   PATRIC; fig|1411691.4.peg.3127; -.
DR   EchoBASE; EB2197; -.
DR   eggNOG; COG0583; Bacteria.
DR   HOGENOM; CLU_039613_16_2_6; -.
DR   OMA; PDDCDIL; -.
DR   PhylomeDB; P37682; -.
DR   BioCyc; EcoCyc:EG12289-MON; -.
DR   PRO; PR:P37682; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..324
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   YiaU"
FT                   /id="PRO_0000105800"
FT   DOMAIN          6..63
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT   DNA_BIND        23..42
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
SQ   SEQUENCE   324 AA;  37274 MW;  21A64718F2EA5DC0 CRC64;
     MTKLQLKYRE LKIISVIAAS ENISHAATVL GIAQANVSKY LADFESKVGL KVFDRTTRQL
     MLTPFGTALL PYINDMLDRN EQLNNFIADY KHEKRGRVTI YAPTGIITYL SKHVIDKIKD
     IGDITLSLKT CNLERNAFYE GVEFPDDCDV LISYAPPKDE SLVASFITQY AVTAYASQRY
     LEKHPISRPD ELEHHSCILI DSMMIDDANI WRFNVAGSKE VRDYRVKGNY VCDNTQSALE
     LARNHLGIVF APDKSVQSDL QDGTLVPCFQ QPYEWWLDLV AIFRKREYQP WRVQYVLDEM
     LREIRHQLAQ SQQLRPEQAA ESED