ID   YIAV_ECOLI              Reviewed;         378 AA.
AC   P37683; Q2M7P9;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   03-AUG-2022, entry version 142.
DE   RecName: Full=Inner membrane protein YiaV;
DE   Flags: Precursor;
GN   Name=yiaV; OrderedLocusNames=b3586, JW3558;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=8041620; DOI=10.1093/nar/22.13.2576;
RA   Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.;
RT   "Analysis of the Escherichia coli genome. V. DNA sequence of the region
RT   from 76.0 to 81.5 minutes.";
RL   Nucleic Acids Res. 22:2576-2586(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [4]
RP   TOPOLOGY [LARGE SCALE ANALYSIS].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=15919996; DOI=10.1126/science.1109730;
RA   Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT   "Global topology analysis of the Escherichia coli inner membrane
RT   proteome.";
RL   Science 308:1321-1323(2005).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000305}.
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DR   EMBL; U00039; AAB18563.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC76610.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77707.1; -; Genomic_DNA.
DR   PIR; S47807; S47807.
DR   RefSeq; NP_418043.1; NC_000913.3.
DR   RefSeq; WP_000364884.1; NZ_STEB01000018.1.
DR   AlphaFoldDB; P37683; -.
DR   SMR; P37683; -.
DR   BioGRID; 4262557; 260.
DR   STRING; 511145.b3586; -.
DR   TCDB; 8.A.1.1.4; the membrane fusion protein (mfp) family.
DR   PaxDb; P37683; -.
DR   PRIDE; P37683; -.
DR   EnsemblBacteria; AAC76610; AAC76610; b3586.
DR   EnsemblBacteria; BAE77707; BAE77707; BAE77707.
DR   GeneID; 66672522; -.
DR   GeneID; 948106; -.
DR   KEGG; ecj:JW3558; -.
DR   KEGG; eco:b3586; -.
DR   PATRIC; fig|1411691.4.peg.3126; -.
DR   EchoBASE; EB2198; -.
DR   eggNOG; COG1566; Bacteria.
DR   HOGENOM; CLU_018816_15_3_6; -.
DR   InParanoid; P37683; -.
DR   OMA; FIPMGWG; -.
DR   PhylomeDB; P37683; -.
DR   BioCyc; EcoCyc:EG12290-MON; -.
DR   PRO; PR:P37683; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   InterPro; IPR043602; CusB_dom_1.
DR   InterPro; IPR032317; HlyD_D23.
DR   Pfam; PF00529; CusB_dom_1; 1.
DR   Pfam; PF16576; HlyD_D23; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome; Signal;
KW   Transmembrane; Transmembrane helix.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000255"
FT   CHAIN           16..378
FT                   /note="Inner membrane protein YiaV"
FT                   /id="PRO_0000018722"
FT   TOPO_DOM        17..26
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        27..47
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        48..56
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        78..378
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   378 AA;  41771 MW;  6683C1E129BC3E53 CRC64;
     MDLLIILTYV AFAWAMFKIF KIPVNKWTIP TAALGGIFIV SGLILLMNYN HPYTFKAQKA
     VISIPVVPQV TGVVIEVTDK KNTLIKKGEV LFRLDPTRYQ ARVDRLMADI VTAEHKQRAL
     GAELDEMAAN TQQAKATRDK FAKEYQRYAR GSQAKVNPFS ERDIDVARQN YLAQEASVKS
     SAAEQKQIQS QLDSLVLGEH SQIASLKAQL AEAKYNLEQT IVRAPSDGYV TQVLIRPGTY
     AASLPLRPVM VFIPDQKRQI VAQFRQNSLL RLAPGDDAEV VFNALPGKVF SGKLAAISPA
     VPGGAYQSTG TLQTLNTAPG SDGVIATIEL DEHTDLSALP DGIYAQVAVY SDHFSHVSVM
     RKVLLRMTSW VHYLYLDH