ID   YICC_ECOLI              Reviewed;         287 AA.
AC   P23839; Q2M7V7;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 2.
DT   03-AUG-2022, entry version 154.
DE   RecName: Full=UPF0701 protein YicC;
GN   Name=yicC; OrderedLocusNames=b3644, JW3619;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RX   PubMed=2664418; DOI=10.1111/j.1365-2958.1989.tb00184.x;
RA   Poulsen P., Andersen J.T., Jensen K.F.;
RT   "Molecular and mutational analysis of three genes preceding pyrE on the
RT   Escherichia coli chromosome.";
RL   Mol. Microbiol. 3:393-404(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=7686882; DOI=10.1006/geno.1993.1230;
RA   Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R.;
RT   "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome:
RT   organizational symmetry around the origin of replication.";
RL   Genomics 16:551-561(1993).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   IMPORTANCE AT HIGH TEMPERATURE.
RX   PubMed=1925027; DOI=10.1016/0923-2508(91)90042-9;
RA   Poulsen P., Jensen K.F.;
RT   "Three genes preceding pyrE on the Escherichia coli chromosome are
RT   essential for survival and normal cell morphology in stationary culture and
RT   at high temperature.";
RL   Res. Microbiol. 142:283-288(1991).
RN   [6]
RP   IDENTIFICATION BY 2D-GEL.
RX   PubMed=9298644; DOI=10.1002/elps.1150180805;
RA   VanBogelen R.A., Abshire K.Z., Moldover B., Olson E.R., Neidhardt F.C.;
RT   "Escherichia coli proteome analysis using the gene-protein database.";
RL   Electrophoresis 18:1243-1251(1997).
CC   -!- MISCELLANEOUS: Essential for E.coli under special growth condition.
CC   -!- SIMILARITY: Belongs to the UPF0701 family. {ECO:0000305}.
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DR   EMBL; X14235; CAA32451.1; -; Genomic_DNA.
DR   EMBL; L10328; AAA61997.1; -; Genomic_DNA.
DR   EMBL; U00096; AAC76668.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77649.1; -; Genomic_DNA.
DR   PIR; F65165; F65165.
DR   RefSeq; NP_418101.1; NC_000913.3.
DR   RefSeq; WP_000621340.1; NZ_SSZK01000022.1.
DR   AlphaFoldDB; P23839; -.
DR   SMR; P23839; -.
DR   BioGRID; 4261234; 29.
DR   DIP; DIP-12428N; -.
DR   IntAct; P23839; 13.
DR   STRING; 511145.b3644; -.
DR   jPOST; P23839; -.
DR   PaxDb; P23839; -.
DR   PRIDE; P23839; -.
DR   DNASU; 948154; -.
DR   EnsemblBacteria; AAC76668; AAC76668; b3644.
DR   EnsemblBacteria; BAE77649; BAE77649; BAE77649.
DR   GeneID; 948154; -.
DR   KEGG; ecj:JW3619; -.
DR   KEGG; eco:b3644; -.
DR   PATRIC; fig|511145.12.peg.3764; -.
DR   EchoBASE; EB1178; -.
DR   eggNOG; COG1561; Bacteria.
DR   HOGENOM; CLU_076609_0_0_6; -.
DR   InParanoid; P23839; -.
DR   OMA; EIKSVNH; -.
DR   PhylomeDB; P23839; -.
DR   BioCyc; EcoCyc:EG11192-MON; -.
DR   PRO; PR:P23839; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005829; C:cytosol; IDA:EcoCyc.
DR   InterPro; IPR005229; CHP00255.
DR   InterPro; IPR013551; DUF1732.
DR   InterPro; IPR013527; YicC-like_N.
DR   PANTHER; PTHR30636; PTHR30636; 1.
DR   Pfam; PF08340; DUF1732; 1.
DR   Pfam; PF03755; YicC_N; 1.
DR   TIGRFAMs; TIGR00255; TIGR00255; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..287
FT                   /note="UPF0701 protein YicC"
FT                   /id="PRO_0000169613"
FT   CONFLICT        148
FT                   /note="E -> Q (in Ref. 1; CAA32451)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        184..189
FT                   /note="RLVAKL -> SGREV (in Ref. 1; CAA32451)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   287 AA;  33175 MW;  7368D35E06FCA3B9 CRC64;
     MIRSMTAYAR REIKGEWGSA TWEMRSVNQR YLETYFRLPE QFRSLEPVVR ERIRSRLTRG
     KVECTLRYEP DVSAQGELIL NEKLAKQLVT AANWVKMQSD EGEINPVDIL RWPGVMAAQE
     QDLDAIAAEI LAALDGTLDD FIVARETEGQ ALKALIEQRL EGVTAEVVKV RSHMPEILQW
     QRERLVAKLE DAQVQLENNR LEQELVLLAQ RIDVAEELDR LEAHVKETYN ILKKKEAVGR
     RLDFMMQEFN RESNTLASKS INAEVTNSAI ELKVLIEQMR EQIQNIE