YICG_ECOLI
ID YICG_ECOLI Reviewed; 205 AA.
AC P0AGM2; P31432; P76720; Q2M7V9;
DT 20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT 20-DEC-2005, sequence version 1.
DT 03-AUG-2022, entry version 103.
DE RecName: Full=UPF0126 inner membrane protein YicG;
GN Name=yicG; OrderedLocusNames=b3646, JW3621;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=7686882; DOI=10.1006/geno.1993.1230;
RA Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R.;
RT "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome:
RT organizational symmetry around the origin of replication.";
RL Genomics 16:551-561(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the UPF0126 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA61999.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; L10328; AAA61999.1; ALT_INIT; Genomic_DNA.
DR EMBL; U00096; AAC76670.2; -; Genomic_DNA.
DR EMBL; AP009048; BAE77647.1; -; Genomic_DNA.
DR PIR; H65165; H65165.
DR RefSeq; NP_418103.4; NC_000913.3.
DR RefSeq; WP_000924289.1; NZ_STEB01000024.1.
DR AlphaFoldDB; P0AGM2; -.
DR SMR; P0AGM2; -.
DR BioGRID; 4262566; 4.
DR STRING; 511145.b3646; -.
DR TCDB; 1.A.62.2.3; the homotrimeric cation channel (tric) family.
DR PaxDb; P0AGM2; -.
DR PRIDE; P0AGM2; -.
DR EnsemblBacteria; AAC76670; AAC76670; b3646.
DR EnsemblBacteria; BAE77647; BAE77647; BAE77647.
DR GeneID; 67417647; -.
DR GeneID; 948165; -.
DR KEGG; ecj:JW3621; -.
DR KEGG; eco:b3646; -.
DR PATRIC; fig|511145.12.peg.3766; -.
DR EchoBASE; EB1634; -.
DR eggNOG; COG2860; Bacteria.
DR HOGENOM; CLU_064906_2_0_6; -.
DR InParanoid; P0AGM2; -.
DR OMA; MPKFDYQ; -.
DR PhylomeDB; P0AGM2; -.
DR BioCyc; EcoCyc:EG11683-MON; -.
DR PRO; PR:P0AGM2; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR InterPro; IPR005115; Gly_transporter.
DR Pfam; PF03458; Gly_transporter; 2.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..205
FT /note="UPF0126 inner membrane protein YicG"
FT /id="PRO_0000166299"
FT TOPO_DOM 1..29
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 30..50
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 51..64
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 86..87
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 88..108
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 109..111
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 133..147
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 169..189
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 190..205
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 205 AA; 22048 MW; 346B73FB373F27C7 CRC64;
MLLHILYLVG ITAEAMTGAL AAGRRRMDTF GVIIIATATA IGGGSVRDIL LGHYPLGWVK
HPEYVIIVAT AAVLTTIVAP VMPYLRKVFL VLDALGLVVF SIIGAQVALD MGHGPIIAVV
AAVTTGVFGG VLRDMFCKRI PLVFQKELYA GVSFASAVLY IALQHYVSNH DVVIISTLVF
GFFARLLALR LKLGLPVFYY SHEGH
