ID   YICG_SHIFL              Reviewed;         205 AA.
AC   P0AGM4; P31432; P76720;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=UPF0126 inner membrane protein YicG;
GN   Name=yicG; OrderedLocusNames=SF3685, S4083;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0126 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAN45132.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAP19060.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE005674; AAN45132.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE014073; AAP19060.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_709425.1; NC_004337.2.
DR   RefSeq; WP_000924289.1; NZ_WPGW01000042.1.
DR   AlphaFoldDB; P0AGM4; -.
DR   SMR; P0AGM4; -.
DR   STRING; 198214.SF3685; -.
DR   EnsemblBacteria; AAN45132; AAN45132; SF3685.
DR   EnsemblBacteria; AAP19060; AAP19060; S4083.
DR   GeneID; 1026237; -.
DR   GeneID; 67417647; -.
DR   KEGG; sfl:SF3685; -.
DR   KEGG; sfx:S4083; -.
DR   PATRIC; fig|198214.7.peg.4349; -.
DR   HOGENOM; CLU_064906_2_0_6; -.
DR   OMA; MPKFDYQ; -.
DR   OrthoDB; 1665397at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005115; Gly_transporter.
DR   Pfam; PF03458; Gly_transporter; 2.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..205
FT                   /note="UPF0126 inner membrane protein YicG"
FT                   /id="PRO_0000166301"
FT   TOPO_DOM        1..29
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        51..64
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        65..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        86..87
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        88..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        109..111
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        112..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        133..147
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        169..189
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        190..205
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   205 AA;  22048 MW;  346B73FB373F27C7 CRC64;
     MLLHILYLVG ITAEAMTGAL AAGRRRMDTF GVIIIATATA IGGGSVRDIL LGHYPLGWVK
     HPEYVIIVAT AAVLTTIVAP VMPYLRKVFL VLDALGLVVF SIIGAQVALD MGHGPIIAVV
     AAVTTGVFGG VLRDMFCKRI PLVFQKELYA GVSFASAVLY IALQHYVSNH DVVIISTLVF
     GFFARLLALR LKLGLPVFYY SHEGH