ID   YIDC_CHLPD              Reviewed;         579 AA.
AC   A1BJZ7;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Membrane protein insertase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE   AltName: Full=Foldase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE   AltName: Full=Membrane integrase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE   AltName: Full=Membrane protein YidC {ECO:0000255|HAMAP-Rule:MF_01810};
GN   Name=yidC {ECO:0000255|HAMAP-Rule:MF_01810};
GN   OrderedLocusNames=Cpha266_2740;
OS   Chlorobium phaeobacteroides (strain DSM 266).
OC   Bacteria; Chlorobi; Chlorobia; Chlorobiales; Chlorobiaceae;
OC   Chlorobium/Pelodictyon group; Chlorobium.
OX   NCBI_TaxID=290317;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 266;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Pitluck S., Goltsman E.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Mikhailova N., Li T.,
RA   Overmann J., Bryant D.A., Richardson P.;
RT   "Complete sequence of Chlorobium phaeobacteroides DSM 266.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the insertion and/or proper folding and/or
CC       complex formation of integral membrane proteins into the membrane.
CC       Involved in integration of membrane proteins that insert both
CC       dependently and independently of the Sec translocase complex, as well
CC       as at least some lipoproteins. Aids folding of multispanning membrane
CC       proteins. {ECO:0000255|HAMAP-Rule:MF_01810}.
CC   -!- SUBUNIT: Interacts with the Sec translocase complex via SecD.
CC       Specifically interacts with transmembrane segments of nascent integral
CC       membrane proteins during membrane integration. {ECO:0000255|HAMAP-
CC       Rule:MF_01810}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01810}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01810}.
CC   -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01810}.
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DR   EMBL; CP000492; ABL66724.1; -; Genomic_DNA.
DR   RefSeq; WP_015961251.1; NC_008639.1.
DR   AlphaFoldDB; A1BJZ7; -.
DR   SMR; A1BJZ7; -.
DR   STRING; 290317.Cpha266_2740; -.
DR   PRIDE; A1BJZ7; -.
DR   EnsemblBacteria; ABL66724; ABL66724; Cpha266_2740.
DR   KEGG; cph:Cpha266_2740; -.
DR   eggNOG; COG0706; Bacteria.
DR   HOGENOM; CLU_016535_2_0_10; -.
DR   OMA; WGIFGWI; -.
DR   OrthoDB; 524437at2; -.
DR   Proteomes; UP000008701; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.70.98.90; -; 1.
DR   HAMAP; MF_01810; YidC_type1; 1.
DR   InterPro; IPR019998; Membr_insert_YidC.
DR   InterPro; IPR028055; Membr_insert_YidC/Oxa1_C.
DR   InterPro; IPR028053; Membr_insert_YidC_N.
DR   InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR   InterPro; IPR038210; YidC_periplasmic.
DR   InterPro; IPR038221; YidC_periplasmic_sf.
DR   PANTHER; PTHR12428; PTHR12428; 1.
DR   Pfam; PF02096; 60KD_IMP; 1.
DR   Pfam; PF14849; YidC_periplas; 1.
DR   PRINTS; PR00701; 60KDINNERMP.
DR   PRINTS; PR01900; YIDCPROTEIN.
DR   TIGRFAMs; TIGR03593; yidC_nterm; 1.
DR   TIGRFAMs; TIGR03592; yidC_oxa1_cterm; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Chaperone; Membrane; Protein transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..579
FT                   /note="Membrane protein insertase YidC"
FT                   /id="PRO_1000070080"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT   TRANSMEM        333..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT   TRANSMEM        362..382
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT   TRANSMEM        427..447
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT   TRANSMEM        473..493
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT   TRANSMEM        520..540
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
SQ   SEQUENCE   579 AA;  64362 MW;  92E4A3B2BF3EC1F0 CRC64;
     MDRNSVTGLA LIAMIMIVWL QFMSPENKPK LRTEPVKKEL ATSAAVTPGA PAAPVGDNLG
     IFATASAGAE QLQTVENDLF KVTLSSKGAT IKSVVLKQHL DGHLKQFNLV STPDKGALSL
     LFLSNDGKKI DTRDLYFRSV SLDTLKTLSG TERYVIRYVL DVTPEKAIAI TYGFSGNSYR
     IDYDVKLTGF NNALVGNEYQ VQWDGGLVYS EKNREDESHN ALAGSYLGGS FVKLDASKDK
     ESYREEQSGL AKWVALRNKY FVAAIIPRGA TEGIFLEGRK TAATHFEDYL AALKMSVSAT
     EPVSSNSYSL YVGPLDYNTV KSLGVDLEKI MDFGWDWLTR PFAEYIILPA FTWMNRFVSN
     YGLIIIIFAL LIKLVTYPLS MASTKSMKKM SALQPALKEL QEKYKDNPAK LQSELGRIYK
     EAGVNPLGGC LPVVLQMPLL FAMFYVFRSS IQLRHHGFLW AKDLSVPDSI LDFGFAIPMY
     GDHIAVFPIL MAITVFVQQK ITPTAQSNEQ MKIMMYMFPA MMLLFFNNLP AGLGLYYLMF
     NIFSVAQQFY INATTTADDM PNVNLGTSSS KKKKAGPKK