YIDC_JANSC
ID YIDC_JANSC Reviewed; 626 AA.
AC Q28UQ8;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 04-APR-2006, sequence version 1.
DT 25-MAY-2022, entry version 83.
DE RecName: Full=Membrane protein insertase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE AltName: Full=Foldase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE AltName: Full=Membrane integrase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE AltName: Full=Membrane protein YidC {ECO:0000255|HAMAP-Rule:MF_01810};
GN Name=yidC {ECO:0000255|HAMAP-Rule:MF_01810}; OrderedLocusNames=Jann_0637;
OS Jannaschia sp. (strain CCS1).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC Roseobacteraceae; Jannaschia; unclassified Jannaschia.
OX NCBI_TaxID=290400;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCS1;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D.,
RA Han C., Tapia R., Gilna P., Chertkov O., Saunders E., Schmutz J.,
RA Larimer F., Land M., Kyrpides N., Lykidis A., Moran M.A., Belas R., Ye W.,
RA Buchan A., Gonzalez J.M., Schell M.A., Richardson P.;
RT "Complete sequence of chromosome of Jannaschia sp. CCS1.";
RL Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the insertion and/or proper folding and/or
CC complex formation of integral membrane proteins into the membrane.
CC Involved in integration of membrane proteins that insert both
CC dependently and independently of the Sec translocase complex, as well
CC as at least some lipoproteins. Aids folding of multispanning membrane
CC proteins. {ECO:0000255|HAMAP-Rule:MF_01810}.
CC -!- SUBUNIT: Interacts with the Sec translocase complex via SecD.
CC Specifically interacts with transmembrane segments of nascent integral
CC membrane proteins during membrane integration. {ECO:0000255|HAMAP-
CC Rule:MF_01810}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01810}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01810}.
CC -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01810}.
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DR EMBL; CP000264; ABD53554.1; -; Genomic_DNA.
DR RefSeq; WP_011453762.1; NC_007802.1.
DR AlphaFoldDB; Q28UQ8; -.
DR SMR; Q28UQ8; -.
DR STRING; 290400.Jann_0637; -.
DR EnsemblBacteria; ABD53554; ABD53554; Jann_0637.
DR KEGG; jan:Jann_0637; -.
DR eggNOG; COG0706; Bacteria.
DR HOGENOM; CLU_016535_1_0_5; -.
DR OMA; INPVAGC; -.
DR OrthoDB; 524437at2; -.
DR Proteomes; UP000008326; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 2.70.98.90; -; 1.
DR HAMAP; MF_01810; YidC_type1; 1.
DR InterPro; IPR019998; Membr_insert_YidC.
DR InterPro; IPR028055; Membr_insert_YidC/Oxa1_C.
DR InterPro; IPR028053; Membr_insert_YidC_N.
DR InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR InterPro; IPR038210; YidC_periplasmic.
DR InterPro; IPR038221; YidC_periplasmic_sf.
DR PANTHER; PTHR12428; PTHR12428; 1.
DR Pfam; PF02096; 60KD_IMP; 1.
DR Pfam; PF14849; YidC_periplas; 1.
DR PRINTS; PR00701; 60KDINNERMP.
DR PRINTS; PR01900; YIDCPROTEIN.
DR TIGRFAMs; TIGR03593; yidC_nterm; 1.
DR TIGRFAMs; TIGR03592; yidC_oxa1_cterm; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Chaperone; Membrane; Protein transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..626
FT /note="Membrane protein insertase YidC"
FT /id="PRO_1000070110"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT TRANSMEM 399..419
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT TRANSMEM 469..489
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT TRANSMEM 527..547
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT TRANSMEM 563..583
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
SQ SEQUENCE 626 AA; 69109 MW; F497202FA5811FA4 CRC64;
MDDQNRNLIL ATGLSFVVIL VWFLLFPPPE MVEDPNAIPP AAETGGVETD TGIALTPPVT
VADAPAGADT TAPSEVALSE AARIDIDTPA VEGSISLLGG RIDDLSLRNY FTEVDGDQIV
RLLSPVGSDD PYYALYGWTP SGDLGYADVP TSDTPWELES GTILTPDSPI TLAWDNGSGL
IFRRTIEIDD RFMFQVTQSV ENTGGAEVNL APYGIVARHG LPSDLQNFFI LHEGVVRKVD
GELSELGYSD LPDLDIIARE GVPAEVMEVE TNGWIGFTDK YWMTTLIPGE NQSFVSVVKY
VPSAEIYQTE ARLPYMSIAP GETAEVTTQL FAGAKEAEAI RDYENAEPGL IASLFGAEQD
ASRGEIPRFI DSIDWGWFYF LTKPLFWLLH WLNGAIGNMG LAIISLTLIV KAVLFPLAYR
SYVSMAKMKE LQPEIEKLKE SAGDDRQKLQ QGMMELYKKN KVNPAGGCLP ILLQIPIFFS
LYKVIFVTLE LRHAPFFGWL NDLSAPDSSS IINLYGLLPN PAPEPESIMA LIFIGILPLL
LGISMWLQQK LNPAPTDAMQ AQIFAWLPWV FMFMLGSFAS GLLVYWIANN TLTFTQQYLI
MRSQGFKPDV FGNIRSSFKK KAKEEK
