ID   YIDC_MARMM              Reviewed;         592 AA.
AC   Q0ASI6;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Membrane protein insertase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE   AltName: Full=Foldase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE   AltName: Full=Membrane integrase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE   AltName: Full=Membrane protein YidC {ECO:0000255|HAMAP-Rule:MF_01810};
GN   Name=yidC {ECO:0000255|HAMAP-Rule:MF_01810}; OrderedLocusNames=Mmar10_0458;
OS   Maricaulis maris (strain MCS10).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Maricaulales; Maricaulaceae;
OC   Maricaulis.
OX   NCBI_TaxID=394221;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MCS10;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Saunders E., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Viollier P.,
RA   Stephens C., Richardson P.;
RT   "Complete sequence of Maricaulis maris MCS10.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for the insertion and/or proper folding and/or
CC       complex formation of integral membrane proteins into the membrane.
CC       Involved in integration of membrane proteins that insert both
CC       dependently and independently of the Sec translocase complex, as well
CC       as at least some lipoproteins. Aids folding of multispanning membrane
CC       proteins. {ECO:0000255|HAMAP-Rule:MF_01810}.
CC   -!- SUBUNIT: Interacts with the Sec translocase complex via SecD.
CC       Specifically interacts with transmembrane segments of nascent integral
CC       membrane proteins during membrane integration. {ECO:0000255|HAMAP-
CC       Rule:MF_01810}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01810}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01810}.
CC   -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01810}.
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DR   EMBL; CP000449; ABI64751.1; -; Genomic_DNA.
DR   RefSeq; WP_011642398.1; NC_008347.1.
DR   AlphaFoldDB; Q0ASI6; -.
DR   SMR; Q0ASI6; -.
DR   STRING; 394221.Mmar10_0458; -.
DR   EnsemblBacteria; ABI64751; ABI64751; Mmar10_0458.
DR   KEGG; mmr:Mmar10_0458; -.
DR   eggNOG; COG0706; Bacteria.
DR   HOGENOM; CLU_016535_1_0_5; -.
DR   OMA; INPVAGC; -.
DR   OrthoDB; 524437at2; -.
DR   Proteomes; UP000001964; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.70.98.90; -; 1.
DR   HAMAP; MF_01810; YidC_type1; 1.
DR   InterPro; IPR019998; Membr_insert_YidC.
DR   InterPro; IPR028055; Membr_insert_YidC/Oxa1_C.
DR   InterPro; IPR028053; Membr_insert_YidC_N.
DR   InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR   InterPro; IPR038210; YidC_periplasmic.
DR   InterPro; IPR038221; YidC_periplasmic_sf.
DR   PANTHER; PTHR12428; PTHR12428; 1.
DR   Pfam; PF02096; 60KD_IMP; 1.
DR   Pfam; PF14849; YidC_periplas; 1.
DR   PRINTS; PR00701; 60KDINNERMP.
DR   PRINTS; PR01900; YIDCPROTEIN.
DR   TIGRFAMs; TIGR03593; yidC_nterm; 1.
DR   TIGRFAMs; TIGR03592; yidC_oxa1_cterm; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Chaperone; Membrane; Protein transport;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..592
FT                   /note="Membrane protein insertase YidC"
FT                   /id="PRO_1000070121"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT   TRANSMEM        363..385
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT   TRANSMEM        430..450
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT   TRANSMEM        493..513
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT   TRANSMEM        531..551
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
SQ   SEQUENCE   592 AA;  65358 MW;  4044C2699D9E1289 CRC64;
     MGEDQRNLFI ALGLILVILT GYQMFVMGPA EEERRAEQAA VEASQELADP DLPASALEPA
     AATTVDRETA LGGNQRVTID APSVLGSLSL TGARLDDVRL RRHTETIDDD TPVALLNPIG
     SDHVFYARDG WTSATSGFTD LPGGSTEWTL ASGSTLTPDT PITLTYDSPS GLHFERVISV
     DDNYLFTLTD TVTNNSGQEV ELSRYGLVRH EGRPEDETRN MAVFEGALAV IDGAMVRSSF
     GKLEDGNQTE ESGTGGWVGI TQRYWMAAAV PDQDRPFTAR FRTIERGEID AFEASYVEQA
     IAVPAGESLA STTRIFAGAK ELGVLQQVQN EVGIERFDMA INWGWLWFLT RPFVWLLTML
     EGALGQFGLA ILALTLMVKI VMFPLANRAY ASMAKMKAVQ PKMAEIKERY GADQQKQQQA
     LMELYKTEKI NPLAGCLPIL PQIPIFFALY QTLFNAIEMR HAPFFGWIRD LSAADPTNIW
     NLFGLIPYDP TGIWLIGGVL GIGAWPIIMG LTMAAQQALN PPPPDPMQAR IFAFLPIVFT
     FILAPFAAGL VIYWAWNNFL SVLQQYIIMR RHGNETQVDK LVARLLKRDR GD