ID   YIDC_MYCGA              Reviewed;         383 AA.
AC   P60035;
DT   21-NOV-2003, integrated into UniProtKB/Swiss-Prot.
DT   21-NOV-2003, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=Membrane protein insertase YidC;
DE   AltName: Full=Foldase YidC;
DE   AltName: Full=Membrane integrase YidC;
DE   AltName: Full=Membrane protein YidC;
GN   Name=yidC; OrderedLocusNames=MYCGA0090; ORFNames=MGA_0631;
OS   Mycoplasma gallisepticum (strain R(low / passage 15 / clone 2))
OS   (Mycoplasmoides gallisepticum).
OC   Bacteria; Tenericutes; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX   NCBI_TaxID=710127;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=R(low / passage 15 / clone 2);
RX   PubMed=12949158; DOI=10.1099/mic.0.26427-0;
RA   Papazisi L., Gorton T.S., Kutish G., Markham P.F., Browning G.F.,
RA   Nguyen D.K., Swartzell S., Madan A., Mahairas G., Geary S.J.;
RT   "The complete genome sequence of the avian pathogen Mycoplasma
RT   gallisepticum strain R(low).";
RL   Microbiology 149:2307-2316(2003).
CC   -!- FUNCTION: Required for the insertion and/or proper folding and/or
CC       complex formation of integral membrane proteins into the membrane.
CC       Involved in integration of membrane proteins that insert both
CC       dependently and independently of the Sec translocase complex, as well
CC       as at least some lipoproteins. Aids folding of multispanning membrane
CC       proteins (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with the Sec translocase complex via SecD.
CC       Specifically interacts with transmembrane segments of nascent integral
CC       membrane proteins during membrane integration (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
CC       {ECO:0000305}.
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DR   EMBL; AE015450; AAP56359.1; -; Genomic_DNA.
DR   RefSeq; WP_011113238.1; NC_004829.2.
DR   AlphaFoldDB; P60035; -.
DR   SMR; P60035; -.
DR   GeneID; 57203286; -.
DR   KEGG; mga:MGA_0631; -.
DR   HOGENOM; CLU_058030_0_0_14; -.
DR   OMA; LMTITRP; -.
DR   OrthoDB; 818983at2; -.
DR   Proteomes; UP000001418; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR028055; Membr_insert_YidC/Oxa1_C.
DR   InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR   PANTHER; PTHR12428; PTHR12428; 1.
DR   Pfam; PF02096; 60KD_IMP; 1.
DR   TIGRFAMs; TIGR03592; yidC_oxa1_cterm; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Chaperone; Membrane; Protein transport; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..383
FT                   /note="Membrane protein insertase YidC"
FT                   /id="PRO_0000124723"
FT   TRANSMEM        39..59
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        112..132
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        148..168
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        219..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        245..265
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        272..292
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        322..342
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        343..363
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   383 AA;  44332 MW;  1A122D88D894B85F CRC64;
     MNKVHSEIKT QSFNPFWNAA TLKEKSRIDP NLKKALSYLW KFLKICVFLF LTVIGLWGCT
     QTYSEPWTVS NPRIGVGLEI GYNYGVTGDY RYDLTSSNIG PYFSFANYQL SYGPFLAWFV
     WPASQIILPI LYQTRVPLTQ GIDYGLNTIL AILILLFIIR LITIGITLNS TLNTERMGEV
     QGKIAEINAK YKNATDTQSK KMKQIEVMHI YKKHKIKPAA LFVQGFVTIP IFLIVYKMVS
     LTRPIKATIL FGIWDLSVTP GTEIISDISR NWVYIFFVLL VVPMQIVSQW LPQFWATRRN
     RNAKTTSQKG LEQLKKTRRI QWILIFVFAL FPVITPSAVG LYWFLNSIFT ILQSYITHVF
     IVKRRQRTKT ISRLDQILNR ELD