YIDC_PSYIN
ID YIDC_PSYIN Reviewed; 566 AA.
AC A1T0M9;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Membrane protein insertase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE AltName: Full=Foldase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE AltName: Full=Membrane integrase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE AltName: Full=Membrane protein YidC {ECO:0000255|HAMAP-Rule:MF_01810};
GN Name=yidC {ECO:0000255|HAMAP-Rule:MF_01810}; OrderedLocusNames=Ping_3611;
OS Psychromonas ingrahamii (strain 37).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC Psychromonadaceae; Psychromonas.
OX NCBI_TaxID=357804;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=37;
RG US DOE Joint Genome Institute;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Thompson L.S., Brettin T., Bruce D., Han C., Tapia R., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Ivanova N., Staley J.,
RA Richardson P.;
RT "Complete sequence of Psychromonas ingrahamii 37.";
RL Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the insertion and/or proper folding and/or
CC complex formation of integral membrane proteins into the membrane.
CC Involved in integration of membrane proteins that insert both
CC dependently and independently of the Sec translocase complex, as well
CC as at least some lipoproteins. Aids folding of multispanning membrane
CC proteins. {ECO:0000255|HAMAP-Rule:MF_01810}.
CC -!- SUBUNIT: Interacts with the Sec translocase complex via SecD.
CC Specifically interacts with transmembrane segments of nascent integral
CC membrane proteins during membrane integration. {ECO:0000255|HAMAP-
CC Rule:MF_01810}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01810}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01810}.
CC -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01810}.
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DR EMBL; CP000510; ABM05294.1; -; Genomic_DNA.
DR RefSeq; WP_011771842.1; NC_008709.1.
DR AlphaFoldDB; A1T0M9; -.
DR SMR; A1T0M9; -.
DR STRING; 357804.Ping_3611; -.
DR EnsemblBacteria; ABM05294; ABM05294; Ping_3611.
DR KEGG; pin:Ping_3611; -.
DR eggNOG; COG0706; Bacteria.
DR HOGENOM; CLU_016535_3_0_6; -.
DR OMA; INPVAGC; -.
DR OrthoDB; 524437at2; -.
DR Proteomes; UP000000639; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 2.70.98.90; -; 1.
DR HAMAP; MF_01810; YidC_type1; 1.
DR InterPro; IPR019998; Membr_insert_YidC.
DR InterPro; IPR028055; Membr_insert_YidC/Oxa1_C.
DR InterPro; IPR028053; Membr_insert_YidC_N.
DR InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR InterPro; IPR038210; YidC_periplasmic.
DR InterPro; IPR038221; YidC_periplasmic_sf.
DR PANTHER; PTHR12428; PTHR12428; 1.
DR Pfam; PF02096; 60KD_IMP; 1.
DR Pfam; PF14849; YidC_periplas; 1.
DR PRINTS; PR00701; 60KDINNERMP.
DR PRINTS; PR01900; YIDCPROTEIN.
DR TIGRFAMs; TIGR03593; yidC_nterm; 1.
DR TIGRFAMs; TIGR03592; yidC_oxa1_cterm; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Chaperone; Membrane; Protein transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..566
FT /note="Membrane protein insertase YidC"
FT /id="PRO_1000070147"
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT TRANSMEM 356..376
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT TRANSMEM 433..453
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT TRANSMEM 471..491
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT TRANSMEM 510..530
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT REGION 30..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 566 AA; 63545 MW; CA916B95FA44BD28 CRC64;
MESQRNLLLL ALLFVSFLLY TAWVEEKTPQ VAPQVQTEQV DSSVPASVAS SANSANLSDG
VPNSPQQSST DATSTELPAS QSVTIANDEL RLTISLVGGD IIKADLLQHD ATLDSDTPYR
LLDSGNGFTY IAQSGLIGQG PDANKNGRPL YDTTDTESVL ADGQAEVSTM LHFVDADGNI
FIKTFTLKRG EYVTNVAYQI ENKTDSPLNV QLYAQLRETL SDDSGSMVMP VYRGGAFSTT
ETRYEKYSFS DMQDGPLQKT TEGGWVAMLQ HYFVSAWIPS PTDQNVLYSN IIQDKEAAIG
FKAPSKTIAP QSVAELETNL WVGPKIQEEM ALVAKNLDLT VDYGWLWFIA QPLFKLLLFF
QGIVGNWGVA IILITFTVKG ALYPLTKAQY TSMAKMRLLQ PKIKELREQF GEDRQKVSKA
MMELYKKEKV NPLGGCFPIL LQMPIFIALY WSLMESVELR HAPFMLWIQD LSVQDPYYIL
PILMGVSMFF IQKMSPTTVQ DPMQQKVMQF MPVIFTFFFL WFPAGLVLYW LMSNVVTLIQ
QTLIYRSFEK KGLHQKEKEP VVLTKK