ID   YIDC_SCHPO              Reviewed;         462 AA.
AC   Q9UTC7;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 127.
DE   RecName: Full=Uncharacterized WD repeat-containing protein C227.12;
GN   ORFNames=SPAC227.12;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
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DR   EMBL; CU329670; CAB61461.1; -; Genomic_DNA.
DR   PIR; T50168; T50168.
DR   RefSeq; NP_592966.1; NM_001018366.2.
DR   AlphaFoldDB; Q9UTC7; -.
DR   SMR; Q9UTC7; -.
DR   BioGRID; 277979; 3.
DR   IntAct; Q9UTC7; 1.
DR   STRING; 4896.SPAC227.12.1; -.
DR   MaxQB; Q9UTC7; -.
DR   PaxDb; Q9UTC7; -.
DR   EnsemblFungi; SPAC227.12.1; SPAC227.12.1:pep; SPAC227.12.
DR   GeneID; 2541477; -.
DR   KEGG; spo:SPAC227.12; -.
DR   PomBase; SPAC227.12; -.
DR   VEuPathDB; FungiDB:SPAC227.12; -.
DR   eggNOG; KOG0272; Eukaryota.
DR   HOGENOM; CLU_000288_57_20_1; -.
DR   InParanoid; Q9UTC7; -.
DR   OMA; LNEPICY; -.
DR   PhylomeDB; Q9UTC7; -.
DR   PRO; PR:Q9UTC7; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:PomBase.
DR   GO; GO:0030621; F:U4 snRNA binding; IBA:GO_Central.
DR   GO; GO:0017070; F:U6 snRNA binding; IBA:GO_Central.
DR   GO; GO:0045292; P:mRNA cis splicing, via spliceosome; ISS:PomBase.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   Gene3D; 2.130.10.10; -; 3.
DR   Gene3D; 4.10.280.110; -; 1.
DR   InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR   InterPro; IPR014906; PRP4-like.
DR   InterPro; IPR036285; PRP4-like_sf.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_repeat.
DR   InterPro; IPR019775; WD40_repeat_CS.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   Pfam; PF08799; PRP4; 1.
DR   Pfam; PF00400; WD40; 7.
DR   PRINTS; PR00320; GPROTEINBRPT.
DR   SMART; SM00500; SFM; 1.
DR   SMART; SM00320; WD40; 7.
DR   SUPFAM; SSF158230; SSF158230; 1.
DR   SUPFAM; SSF50978; SSF50978; 1.
DR   PROSITE; PS00678; WD_REPEATS_1; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 6.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   4: Predicted;
KW   Cytoplasm; Reference proteome; Repeat; WD repeat.
FT   CHAIN           1..462
FT                   /note="Uncharacterized WD repeat-containing protein
FT                   C227.12"
FT                   /id="PRO_0000316560"
FT   REPEAT          170..209
FT                   /note="WD 1"
FT   REPEAT          212..260
FT                   /note="WD 2"
FT   REPEAT          263..302
FT                   /note="WD 3"
FT   REPEAT          305..344
FT                   /note="WD 4"
FT   REPEAT          347..386
FT                   /note="WD 5"
FT   REPEAT          389..430
FT                   /note="WD 6"
FT   REPEAT          433..462
FT                   /note="WD 7"
SQ   SEQUENCE   462 AA;  51746 MW;  4D3703820FF54067 CRC64;
     MNENEGISLG ELETRPFSEG ITRFTKEQAA YYAEQKEKDR IKALKIPYED SKVREYLRRY
     GEPITYFGED ALARRQRLQQ LMIEKSLEGD NPLDVDQGAS ENIEKETYVQ GSHELLVARK
     KIALYSLEKA KLRLKKEREI SEIPVPEIVL SGKSSIEHLQ KAELMGSQIG GERPIAIVRF
     SNNGNHFASG SWGGQVKVWN SDNLSEVQLF RGHTDRVSGL DWYPLCQAWD ADSEQLTLAT
     GAADNTVCLW KASQSTPLLR LEGHLARVGR VAFHPSGDYL VSASFDTTWR LWDVHTGVEL
     LMQEGHSEGI FSIACQPDGS LVSSGGNDAI GRIWDLRSGK SIMVLDEHIR QIVAMAWSPN
     GYQLATSSAD DTVKIWDLRK VSLAHTIPAH SSLVSDVRYI ESGVNRFIAT SGYDGCVKLW
     NPLNCSLIKS MVGHEEKVMS VDGYGDRFIS SGYDRTIKLW YP