YIDC_SHESR
ID YIDC_SHESR Reviewed; 541 AA.
AC Q0HPE6;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 03-OCT-2006, sequence version 1.
DT 25-MAY-2022, entry version 77.
DE RecName: Full=Membrane protein insertase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE AltName: Full=Foldase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE AltName: Full=Membrane integrase YidC {ECO:0000255|HAMAP-Rule:MF_01810};
DE AltName: Full=Membrane protein YidC {ECO:0000255|HAMAP-Rule:MF_01810};
GN Name=yidC {ECO:0000255|HAMAP-Rule:MF_01810};
GN OrderedLocusNames=Shewmr7_4032;
OS Shewanella sp. (strain MR-7).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC Shewanellaceae; Shewanella.
OX NCBI_TaxID=60481;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MR-7;
RA Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Nealson K.,
RA Konstantinidis K., Klappenbach J., Tiedje J., Richardson P.;
RT "Complete sequence of chromosome 1 of Shewanella sp. MR-7.";
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for the insertion and/or proper folding and/or
CC complex formation of integral membrane proteins into the membrane.
CC Involved in integration of membrane proteins that insert both
CC dependently and independently of the Sec translocase complex, as well
CC as at least some lipoproteins. Aids folding of multispanning membrane
CC proteins. {ECO:0000255|HAMAP-Rule:MF_01810}.
CC -!- SUBUNIT: Interacts with the Sec translocase complex via SecD.
CC Specifically interacts with transmembrane segments of nascent integral
CC membrane proteins during membrane integration. {ECO:0000255|HAMAP-
CC Rule:MF_01810}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_01810}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_01810}.
CC -!- SIMILARITY: Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01810}.
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DR EMBL; CP000444; ABI45009.1; -; Genomic_DNA.
DR RefSeq; WP_011627720.1; NC_008322.1.
DR AlphaFoldDB; Q0HPE6; -.
DR SMR; Q0HPE6; -.
DR EnsemblBacteria; ABI45009; ABI45009; Shewmr7_4032.
DR KEGG; shm:Shewmr7_4032; -.
DR HOGENOM; CLU_016535_3_0_6; -.
DR OMA; INPVAGC; -.
DR OrthoDB; 524437at2; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0032977; F:membrane insertase activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 2.70.98.90; -; 1.
DR HAMAP; MF_01810; YidC_type1; 1.
DR InterPro; IPR019998; Membr_insert_YidC.
DR InterPro; IPR028055; Membr_insert_YidC/Oxa1_C.
DR InterPro; IPR028053; Membr_insert_YidC_N.
DR InterPro; IPR001708; YidC/ALB3/OXA1/COX18.
DR InterPro; IPR038210; YidC_periplasmic.
DR InterPro; IPR038221; YidC_periplasmic_sf.
DR PANTHER; PTHR12428; PTHR12428; 1.
DR Pfam; PF02096; 60KD_IMP; 1.
DR Pfam; PF14849; YidC_periplas; 1.
DR PRINTS; PR00701; 60KDINNERMP.
DR PRINTS; PR01900; YIDCPROTEIN.
DR TIGRFAMs; TIGR03593; yidC_nterm; 1.
DR TIGRFAMs; TIGR03592; yidC_oxa1_cterm; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Chaperone; Membrane; Protein transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..541
FT /note="Membrane protein insertase YidC"
FT /id="PRO_1000070174"
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT TRANSMEM 349..369
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT TRANSMEM 420..440
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT TRANSMEM 457..477
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
FT TRANSMEM 500..520
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01810"
SQ SEQUENCE 541 AA; 60573 MW; EE60A2F942B564D2 CRC64;
MESQRNILLI GLLFVSFLLW QQWQADKAPK PVATESSVVA NATTNHSADV PEADTGVPAA
MTATQNLITV KTDQLDVQIN PVGGDIVFAA LVSHKLEQGK DQPFVLLEQT KDFTYIAQSG
LIGRDGIDSS AKGRAAFAAS KTEFTLADGQ DTLEVPLTYV ADNGVTYTKV FVFHRGKFNV
DIDYKINNTS AAPLQVQMYG QIKQTIKPSE SSMMMPTYRG AAFSTQDVRY EKYKFEDMSK
SNLNQPTLGG WAAMLQHYFV SAWIPPATDS NTIFSSVSAG GLANIGFRGA VYDIAPGATQ
EISSQFYVGP KDQKALSALS DTLNLVVDYG FLWWLAVPIH WLLMFYQSFV GNWGVAIILI
TLTVRGLLFP LTKAQYTSMA KMRNLQPKLQ DLKERFGDDR QKMGQAMMEL YKKEKVNPMG
GCLPILLQMP IFIALYWVLL ESFELRHAPF MLWIHDLSVQ DPYYILPLLM GVSMFVMQKM
QPIAPTMDPM QVKMMQWMPV IFTVFFLWFP SGLVLYWLVG NIVAIIQQKI IYAGLEKKGL
K