YIDD_ECOLI
ID YIDD_ECOLI Reviewed; 85 AA.
AC P0A8C8; P22847; Q2EET9; Q2M817;
DT 07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2005, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Putative membrane protein insertion efficiency factor {ECO:0000255|HAMAP-Rule:MF_00386};
GN Name=yidD {ECO:0000255|HAMAP-Rule:MF_00386};
GN OrderedLocusNames=b4557, JW3682;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RX PubMed=2415431; DOI=10.1016/0378-1119(85)90206-9;
RA Hansen F.G., Hansen E.B., Atlung T.;
RT "Physical mapping and nucleotide sequence of the rnpA gene that encodes the
RT protein component of ribonuclease P in Escherichia coli.";
RL Gene 38:85-93(1985).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP FUNCTION IN MEMBRANE PROTEIN INSERTION, SUBCELLULAR LOCATION, AND
RP DISRUPTION PHENOTYPE.
RC STRAIN=K12 / MC4100 / ATCC 35695 / DSM 6574;
RX PubMed=21803992; DOI=10.1128/jb.05429-11;
RA Yu Z., Laven M., Klepsch M., de Gier J.W., Bitter W., van Ulsen P.,
RA Luirink J.;
RT "Role for Escherichia coli YidD in membrane protein insertion.";
RL J. Bacteriol. 193:5242-5251(2011).
CC -!- FUNCTION: Could be involved in insertion of integral membrane proteins
CC into the membrane. {ECO:0000255|HAMAP-Rule:MF_00386,
CC ECO:0000269|PubMed:21803992}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00386, ECO:0000269|PubMed:21803992}; Peripheral membrane
CC protein {ECO:0000255|HAMAP-Rule:MF_00386, ECO:0000269|PubMed:21803992};
CC Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_00386,
CC ECO:0000269|PubMed:21803992}. Note=Associated with the inner membrane
CC via a putative N-terminal amphipathic helix.
CC -!- DISRUPTION PHENOTYPE: Cells lacking this gene are viable with no
CC apparent phenotype, but they are affected in the insertion and
CC processing of three YidC-dependent inner membrane proteins.
CC {ECO:0000269|PubMed:21803992}.
CC -!- SIMILARITY: Belongs to the UPF0161 family. {ECO:0000255|HAMAP-
CC Rule:MF_00386}.
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DR EMBL; M11056; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; U00096; ABD18707.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE77589.1; -; Genomic_DNA.
DR RefSeq; WP_001307474.1; NZ_STEB01000015.1.
DR RefSeq; YP_588472.1; NC_000913.3.
DR AlphaFoldDB; P0A8C8; -.
DR STRING; 511145.b4557; -.
DR PaxDb; P0A8C8; -.
DR PRIDE; P0A8C8; -.
DR EnsemblBacteria; ABD18707; ABD18707; b4557.
DR EnsemblBacteria; BAE77589; BAE77589; BAE77589.
DR GeneID; 1450303; -.
DR GeneID; 64726507; -.
DR GeneID; 67464395; -.
DR KEGG; ecj:JW3682; -.
DR KEGG; eco:b4557; -.
DR PATRIC; fig|83333.103.peg.3; -.
DR EchoBASE; EB1324; -.
DR eggNOG; COG0759; Bacteria.
DR HOGENOM; CLU_144811_5_2_6; -.
DR InParanoid; P0A8C8; -.
DR OMA; QPTCSHY; -.
DR PhylomeDB; P0A8C8; -.
DR BioCyc; EcoCyc:MON0-2692; -.
DR PRO; PR:P0A8C8; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IDA:EcoCyc.
DR GO; GO:0032977; F:membrane insertase activity; IMP:EcoCyc.
DR GO; GO:0051205; P:protein insertion into membrane; IMP:EcoCyc.
DR HAMAP; MF_00386; UPF0161_YidD; 1.
DR InterPro; IPR002696; Membr_insert_effic_factor.
DR PANTHER; PTHR33383; PTHR33383; 1.
DR Pfam; PF01809; YidD; 1.
DR SMART; SM01234; Haemolytic; 1.
DR TIGRFAMs; TIGR00278; TIGR00278; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome.
FT CHAIN 1..85
FT /note="Putative membrane protein insertion efficiency
FT factor"
FT /id="PRO_0000171821"
SQ SEQUENCE 85 AA; 9381 MW; DCD2A8E612D12348 CRC64;
MAPPLSPGSR VLIALIRVYQ RLISPLLGPH CRFTPTCSSY GIEALRRFGV IKGSWLTVKR
VLKCHPLHPG GDDPVPPGPF DTREH
