ID   CBID_PSEAE              Reviewed;         366 AA.
AC   Q9HZT9;
DT   07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Cobalt-precorrin-5B C(1)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_00787};
DE            EC=2.1.1.195 {ECO:0000255|HAMAP-Rule:MF_00787};
DE   AltName: Full=Cobalt-precorrin-6A synthase {ECO:0000255|HAMAP-Rule:MF_00787};
GN   Name=cbiD {ECO:0000255|HAMAP-Rule:MF_00787}; OrderedLocusNames=PA2908;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: Catalyzes the methylation of C-1 in cobalt-precorrin-5B to
CC       form cobalt-precorrin-6A. {ECO:0000255|HAMAP-Rule:MF_00787}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Co-precorrin-5B + S-adenosyl-L-methionine = Co-precorrin-6A +
CC         S-adenosyl-L-homocysteine; Xref=Rhea:RHEA:26285, ChEBI:CHEBI:57856,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:60063, ChEBI:CHEBI:60064;
CC         EC=2.1.1.195; Evidence={ECO:0000255|HAMAP-Rule:MF_00787};
CC   -!- PATHWAY: Cofactor biosynthesis; adenosylcobalamin biosynthesis;
CC       cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route):
CC       step 6/10. {ECO:0000255|HAMAP-Rule:MF_00787}.
CC   -!- SIMILARITY: Belongs to the CbiD family. {ECO:0000255|HAMAP-
CC       Rule:MF_00787}.
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DR   EMBL; AE004091; AAG06296.1; -; Genomic_DNA.
DR   PIR; F83281; F83281.
DR   RefSeq; NP_251598.1; NC_002516.2.
DR   RefSeq; WP_003114022.1; NZ_QZGE01000009.1.
DR   AlphaFoldDB; Q9HZT9; -.
DR   SMR; Q9HZT9; -.
DR   STRING; 287.DR97_5033; -.
DR   PaxDb; Q9HZT9; -.
DR   EnsemblBacteria; AAG06296; AAG06296; PA2908.
DR   GeneID; 882679; -.
DR   KEGG; pae:PA2908; -.
DR   PATRIC; fig|208964.12.peg.3049; -.
DR   PseudoCAP; PA2908; -.
DR   HOGENOM; CLU_041273_0_0_6; -.
DR   InParanoid; Q9HZT9; -.
DR   OMA; YHGKLIK; -.
DR   PhylomeDB; Q9HZT9; -.
DR   BioCyc; PAER208964:G1FZ6-2958-MON; -.
DR   UniPathway; UPA00148; UER00227.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0043780; F:cobalt-precorrin-5B C1-methyltransferase activity; IEA:RHEA.
DR   GO; GO:0009236; P:cobalamin biosynthetic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0046140; P:corrin biosynthetic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.2110.10; -; 1.
DR   HAMAP; MF_00787; CbiD; 1.
DR   InterPro; IPR002748; CbiD.
DR   InterPro; IPR036074; CbiD_sf.
DR   PANTHER; PTHR35863; PTHR35863; 1.
DR   Pfam; PF01888; CbiD; 1.
DR   PIRSF; PIRSF026782; CbiD; 1.
DR   SUPFAM; SSF111342; SSF111342; 1.
DR   TIGRFAMs; TIGR00312; cbiD; 1.
PE   3: Inferred from homology;
KW   Cobalamin biosynthesis; Methyltransferase; Reference proteome;
KW   S-adenosyl-L-methionine; Transferase.
FT   CHAIN           1..366
FT                   /note="Cobalt-precorrin-5B C(1)-methyltransferase"
FT                   /id="PRO_0000141678"
SQ   SEQUENCE   366 AA;  38146 MW;  3DB271F6AB557115 CRC64;
     MREETPEQPA PLRSGYTTGS CATATSLAAA RLLLGGTISD AVQIVLPKGQ QVLMRLEFCR
     AWENGAEAGT LKDAGDDPDV THGALVFARV RLSAEPGVRF HAGPGVGTVT RPGLTLAVGE
     PAINPVPRQM IERHLAQLAA ERGYAGGFEV AIGVEGGAEL ALKTMNPRLG ILGGLSILGT
     SGIVRPFSCS AYIASIHQGI DVARANGVRH IAACTGNASE DAMRRRYALP EIALIEMGDF
     AGAVLKHLRR APVEKLSLCG GFGKISKLAG GHLDLHSRHS SIDLPQLAGW AAALGASTAL
     QDSMRAANTS QQALAQAHAE GVALGDAVCA HALRFARGIV PTEVALEVFA IDRQGNLVGQ
     ACEERR