YIDK_ECOLI
ID YIDK_ECOLI Reviewed; 571 AA.
AC P31448; Q2M7Z2;
DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1993, sequence version 1.
DT 03-AUG-2022, entry version 156.
DE RecName: Full=Uncharacterized symporter YidK;
GN Name=yidK; OrderedLocusNames=b3679, JW3655;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=7686882; DOI=10.1006/geno.1993.1230;
RA Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R.;
RT "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome:
RT organizational symmetry around the origin of replication.";
RL Genomics 16:551-561(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21)
CC family. {ECO:0000305}.
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DR EMBL; L10328; AAA62031.1; -; Genomic_DNA.
DR EMBL; U00096; AAC76702.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE77614.1; -; Genomic_DNA.
DR PIR; H65169; H65169.
DR RefSeq; NP_418135.1; NC_000913.3.
DR RefSeq; WP_001087145.1; NZ_SSZK01000035.1.
DR AlphaFoldDB; P31448; -.
DR SMR; P31448; -.
DR BioGRID; 4261452; 162.
DR DIP; DIP-12450N; -.
DR IntAct; P31448; 5.
DR STRING; 511145.b3679; -.
DR TCDB; 2.A.21.3.21; the solute:sodium symporter (sss) family.
DR PaxDb; P31448; -.
DR PRIDE; P31448; -.
DR EnsemblBacteria; AAC76702; AAC76702; b3679.
DR EnsemblBacteria; BAE77614; BAE77614; BAE77614.
DR GeneID; 948185; -.
DR KEGG; ecj:JW3655; -.
DR KEGG; eco:b3679; -.
DR PATRIC; fig|1411691.4.peg.3025; -.
DR EchoBASE; EB1657; -.
DR eggNOG; COG4146; Bacteria.
DR HOGENOM; CLU_018808_9_3_6; -.
DR InParanoid; P31448; -.
DR OMA; MFFVVMP; -.
DR PhylomeDB; P31448; -.
DR BioCyc; EcoCyc:YIDK-MON; -.
DR PRO; PR:P31448; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0005412; F:glucose:sodium symporter activity; IBA:GO_Central.
DR Gene3D; 1.20.1730.10; -; 1.
DR InterPro; IPR038377; Na/Glc_symporter_sf.
DR InterPro; IPR001734; Na/solute_symporter.
DR InterPro; IPR018212; Na/solute_symporter_CS.
DR Pfam; PF00474; SSF; 1.
DR TIGRFAMs; TIGR00813; sss; 1.
DR PROSITE; PS00456; NA_SOLUT_SYMP_1; 1.
DR PROSITE; PS50283; NA_SOLUT_SYMP_3; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Ion transport; Membrane;
KW Reference proteome; Sodium; Sodium transport; Symport; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..571
FT /note="Uncharacterized symporter YidK"
FT /id="PRO_0000105406"
FT TOPO_DOM 1..3
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 4..24
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 25..74
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 75..95
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 96..118
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 140..162
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 163..183
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 184..191
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 192..212
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 213..240
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 241..261
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 262..283
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 305..324
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 325..345
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 346..380
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 381..401
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 402..415
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 416..436
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 437
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 438..458
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 459..460
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 461..481
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 482..505
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 506..526
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 527..532
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 533..553
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 554..571
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 571 AA; 62085 MW; 486AB89A6A2EACCF CRC64;
MNSLQILSFV GFTLLVAVIT WWKVRKTDTG SQQGYFLAGR SLKAPVIAAS LMLTNLSTEQ
LVGLSGQAYK SGMSVMGWEV TSAVTLIFLA LIFLPRYLKR GIATIPDFLE ERYDKTTRII
IDFCFLIATG VCFLPIVLYS GALALNSLFH VGESLQISHG AAIWLLVILL GLAGILYAVI
GGLRAMAVAD SINGIGLVIG GLMVPVFGLI AMGKGSFMQG IEQLTTVHAE KLNSIGGPTD
PLPIGAAFTG LILVNTFYWC TNQGIVQRTL ASKSLAEGQK GALLTAVLKM LDPLVLVLPG
LIAFHLYQDL PKADMAYPTL VNNVLPVPMV GFFGAVLFGA VISTFNGFLN SASTLFSMGI
YRRIINQNAE PQQLVTVGRK FGFFIAIVSV LVAPWIANAP QGLYSWMKQL NGIYNVPLVT
IIIMGFFFPR IPALAAKVAM GIGIISYITI NYLVKFDFHF LYVLACTFCI NVVVMLVIGF
IKPRATPFTF KDAFAVDMKP WKNVKIASIG ILFAMIGVYA GLAEFGGYGT RWLAMISYFI
AAVVIVYLIF DSWRHRHDPA VTFTPDGKDS L
