ID   YIEK_ECOLI              Reviewed;         240 AA.
AC   P31470; Q2M836; Q6BF12;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 3.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=Uncharacterized protein YieK;
GN   Name=yieK; OrderedLocusNames=b3718, JW5613;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=7686882; DOI=10.1006/geno.1993.1230;
RA   Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R.;
RT   "DNA sequence and analysis of 136 kilobases of the Escherichia coli genome:
RT   organizational symmetry around the origin of replication.";
RL   Genomics 16:551-561(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND SEQUENCE REVISION TO
RP   N-TERMINUS.
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   SEQUENCE REVISION.
RX   PubMed=16397293; DOI=10.1093/nar/gkj405;
RA   Riley M., Abe T., Arnaud M.B., Berlyn M.K.B., Blattner F.R.,
RA   Chaudhuri R.R., Glasner J.D., Horiuchi T., Keseler I.M., Kosuge T.,
RA   Mori H., Perna N.T., Plunkett G. III, Rudd K.E., Serres M.H., Thomas G.H.,
RA   Thomson N.R., Wishart D., Wanner B.L.;
RT   "Escherichia coli K-12: a cooperatively developed annotation snapshot
RT   -- 2005.";
RL   Nucleic Acids Res. 34:1-9(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SIMILARITY: Belongs to the glucosamine/galactosamine-6-phosphate
CC       isomerase family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA62069.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; L10328; AAA62069.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; U00096; AAT48202.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77570.1; -; Genomic_DNA.
DR   RefSeq; WP_000766900.1; NZ_STEB01000015.1.
DR   RefSeq; YP_026242.1; NC_000913.3.
DR   AlphaFoldDB; P31470; -.
DR   SMR; P31470; -.
DR   BioGRID; 4263200; 3.
DR   STRING; 511145.b3718; -.
DR   PaxDb; P31470; -.
DR   PRIDE; P31470; -.
DR   EnsemblBacteria; AAT48202; AAT48202; b3718.
DR   EnsemblBacteria; BAE77570; BAE77570; BAE77570.
DR   GeneID; 66672382; -.
DR   GeneID; 948229; -.
DR   KEGG; ecj:JW5613; -.
DR   KEGG; eco:b3718; -.
DR   PATRIC; fig|1411691.4.peg.2983; -.
DR   EchoBASE; EB1679; -.
DR   eggNOG; COG0363; Bacteria.
DR   HOGENOM; CLU_049611_1_1_6; -.
DR   InParanoid; P31470; -.
DR   OMA; YQDKKVH; -.
DR   PhylomeDB; P31470; -.
DR   BioCyc; EcoCyc:EG11728-MON; -.
DR   PRO; PR:P31470; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0004342; F:glucosamine-6-phosphate deaminase activity; IBA:GO_Central.
DR   GO; GO:0042802; F:identical protein binding; IBA:GO_Central.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006043; P:glucosamine catabolic process; IBA:GO_Central.
DR   GO; GO:0006046; P:N-acetylglucosamine catabolic process; IBA:GO_Central.
DR   GO; GO:0019262; P:N-acetylneuraminate catabolic process; IBA:GO_Central.
DR   CDD; cd01399; GlcN6P_deaminase; 1.
DR   InterPro; IPR006148; Glc/Gal-6P_isomerase.
DR   InterPro; IPR004547; Glucosamine6P_isomerase.
DR   InterPro; IPR018321; Glucosamine6P_isomerase_CS.
DR   InterPro; IPR037171; NagB/RpiA_transferase-like.
DR   PANTHER; PTHR11280; PTHR11280; 1.
DR   Pfam; PF01182; Glucosamine_iso; 1.
DR   SUPFAM; SSF100950; SSF100950; 1.
DR   PROSITE; PS01161; GLC_GALNAC_ISOMERASE; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..240
FT                   /note="Uncharacterized protein YieK"
FT                   /id="PRO_0000160191"
FT   ACT_SITE        66
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        129
FT                   /evidence="ECO:0000250"
FT   ACT_SITE        131
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000250"
FT   CONFLICT        233..240
FT                   /note="AAAELALG -> VPQN (in Ref. 1; AAA62069)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   240 AA;  26279 MW;  EAFCCFC194DE4481 CRC64;
     MKLIITEDYQ EMSRVAAHHL LGYMSKTRRV NLAITAGSTP KGMYEYLTTL VKGKPWYDNC
     YFYNFDEIPF RGKEGEGVTI TNLRNLFFTP AGIKEENIQK LTIDNYREHD QKLAREGGLD
     LVVLGLGADG HFCGNLPNTT HFHEQTVEFP IQGEMVDIVA HGELGGDFSL VPDSYVTMGP
     KSIMAAKNLL IIVSGAGKAQ ALKNVLQGPV TEDVPASVLQ LHPSLMVIAD KAAAAELALG