ID   YIF1A_DANRE             Reviewed;         307 AA.
AC   Q6PC24; Q7ZV12;
DT   02-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 107.
DE   RecName: Full=Protein YIF1A;
DE   AltName: Full=YIP1-interacting factor homolog A;
GN   Name=yif1a; ORFNames=zgc:73136;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo, and Eye;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Possible role in transport between endoplasmic reticulum and
CC       Golgi. {ECO:0000250|UniProtKB:O95070}.
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC       {ECO:0000250|UniProtKB:O95070}; Multi-pass membrane protein
CC       {ECO:0000255}. Golgi apparatus membrane {ECO:0000250|UniProtKB:O95070};
CC       Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum-Golgi
CC       intermediate compartment membrane {ECO:0000250|UniProtKB:O95070};
CC       Multi-pass membrane protein {ECO:0000255}. Note=Cycles between the
CC       endoplasmic reticulum and the endoplasmic reticulum-Golgi intermediate
CC       compartment. {ECO:0000250|UniProtKB:O95070}.
CC   -!- SIMILARITY: Belongs to the YIF1 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAH46046.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; BC046046; AAH46046.1; ALT_INIT; mRNA.
DR   EMBL; BC059499; AAH59499.1; -; mRNA.
DR   EMBL; BC071433; AAH71433.1; -; mRNA.
DR   RefSeq; NP_956225.1; NM_199931.1.
DR   RefSeq; XP_009289368.1; XM_009291093.1.
DR   RefSeq; XP_017214480.1; XM_017358991.1.
DR   AlphaFoldDB; Q6PC24; -.
DR   STRING; 7955.ENSDARP00000115104; -.
DR   PaxDb; Q6PC24; -.
DR   Ensembl; ENSDART00000009385; ENSDARP00000018303; ENSDARG00000019636.
DR   Ensembl; ENSDART00000137782; ENSDARP00000115104; ENSDARG00000019636.
DR   GeneID; 334982; -.
DR   KEGG; dre:334982; -.
DR   CTD; 10897; -.
DR   ZFIN; ZDB-GENE-030131-6922; yif1a.
DR   eggNOG; KOG3094; Eukaryota.
DR   GeneTree; ENSGT00390000009423; -.
DR   HOGENOM; CLU_047877_1_1_1; -.
DR   InParanoid; Q6PC24; -.
DR   OMA; SHYFQVS; -.
DR   OrthoDB; 1256839at2759; -.
DR   PhylomeDB; Q6PC24; -.
DR   TreeFam; TF314528; -.
DR   PRO; PR:Q6PC24; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 14.
DR   Bgee; ENSDARG00000019636; Expressed in ovary and 32 other tissues.
DR   ExpressionAtlas; Q6PC24; baseline and differential.
DR   GO; GO:0030134; C:COPII-coated ER to Golgi transport vesicle; IBA:GO_Central.
DR   GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR   GO; GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IBA:GO_Central.
DR   GO; GO:0033116; C:endoplasmic reticulum-Golgi intermediate compartment membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR   GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR005578; Yif1_fam.
DR   PANTHER; PTHR14083; PTHR14083; 1.
DR   Pfam; PF03878; YIF1; 1.
PE   2: Evidence at transcript level;
KW   Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; Membrane;
KW   Protein transport; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..307
FT                   /note="Protein YIF1A"
FT                   /id="PRO_0000233277"
FT   TOPO_DOM        1..148
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        170..184
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        206..213
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        214..236
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        237..239
FT                   /note="Lumenal"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        240..259
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        260..285
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000305"
FT   TRANSMEM        286..306
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   307 AA;  34257 MW;  5C7B0230FAD6B20F CRC64;
     MNFQQQGYRA TKPRARASPP TGGPMLFDDT SSGPPPMNNQ NYYSSGYNMA EMPAGGQEPG
     VGNIFADPMA NAAMMYGSTL ANQGKDIVNK EINRFMSVNK LKYFFAVDTK YVMKKLLLLM
     FPYTHQDWEV RYHRDTPLTP RHDVNAPDLY IPTMAFITYI LLAGMALGIQ KRFSPEVLGL
     CASTALVWMI IEVLVMLLSL YLLTVHTDLS TFDLVAYSGY KYVGMILTVF CGLLFGSDGY
     YVALAWSSCA LMFFIVRSLK MKILSSISAD SMGAGASAKP RFRLYITVAS AAFQPFIIYW
     LTAHLVR