YIFC_SCHPO
ID YIFC_SCHPO Reviewed; 996 AA.
AC Q9P7S1; O42705;
DT 29-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=PDZ domain-containing protein C23G3.12c;
GN ORFNames=SPAC23G3.12c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 606-996.
RA Kawamukai M.;
RT "S.pombe YNL123w homolog.";
RL Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase S1C family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU329670; CAB72237.1; -; Genomic_DNA.
DR EMBL; AB010900; BAA24801.1; -; mRNA.
DR PIR; T43318; T43318.
DR PIR; T50186; T50186.
DR RefSeq; NP_593112.1; NM_001018509.2.
DR AlphaFoldDB; Q9P7S1; -.
DR SMR; Q9P7S1; -.
DR BioGRID; 278303; 10.
DR STRING; 4896.SPAC23G3.12c.1; -.
DR iPTMnet; Q9P7S1; -.
DR MaxQB; Q9P7S1; -.
DR PaxDb; Q9P7S1; -.
DR PRIDE; Q9P7S1; -.
DR EnsemblFungi; SPAC23G3.12c.1; SPAC23G3.12c.1:pep; SPAC23G3.12c.
DR GeneID; 2541812; -.
DR KEGG; spo:SPAC23G3.12c; -.
DR PomBase; SPAC23G3.12c; -.
DR VEuPathDB; FungiDB:SPAC23G3.12c; -.
DR eggNOG; KOG1421; Eukaryota.
DR HOGENOM; CLU_003212_0_0_1; -.
DR InParanoid; Q9P7S1; -.
DR OMA; CVFDNHE; -.
DR PhylomeDB; Q9P7S1; -.
DR PRO; PR:Q9P7S1; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0004252; F:serine-type endopeptidase activity; ISM:PomBase.
DR GO; GO:0044255; P:cellular lipid metabolic process; ISO:PomBase.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 2.30.42.10; -; 2.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR025926; PDZ-like_dom.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR001940; Peptidase_S1C.
DR Pfam; PF12812; PDZ_1; 2.
DR PRINTS; PR00834; PROTEASES2C.
DR SMART; SM00228; PDZ; 3.
DR SUPFAM; SSF50156; SSF50156; 3.
DR SUPFAM; SSF50494; SSF50494; 2.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat.
FT CHAIN 1..996
FT /note="PDZ domain-containing protein C23G3.12c"
FT /id="PRO_0000116790"
FT DOMAIN 280..358
FT /note="PDZ 1"
FT DOMAIN 745..827
FT /note="PDZ 2"
FT DOMAIN 860..930
FT /note="PDZ 3"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 972..996
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 7..34
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 996 AA; 110408 MW; A008E51746B05AC3 CRC64;
MSIKKRARAG SKSDDIGNKT PKKNGIEHEA TKSSETVIEM TPSGPIAESK KWKESIARVV
KSVVSIRFSQ VAAFDTDESG TGEASAFVVD AKNGYMLTNR HVVCAGPFVG HAVFDNHEEV
EVFPVYRDPV HDFGFLRFDP KKIRYMNVEQ LELRPDLAKV GTEIRVVGND AAEKLSILAG
WISRIDRNVP DYGELTYCDF NTNYIQAAAN ASGGSSGSPV VERNGNVVAL QAGGHMIAAT
DYFLPLDRPL RALRCLQNNT PITRGTIQAQ FLIKTFDECS RLGLDSAMEE KVRTLFPEAT
SMLVVETVLP EGPSFKKLKE GDILLYVNSM ILINLIELES ILDESVGKDV VLTVQRGSEL
VELTCTAQST HDIAPDRYVE VCGAKFHNLS YQLARQYALP VKGVFISEPA GSFRLEGPEY
GYILDSIAYK PVPDLDTFIE VMRDIPDRSR VAVGYHFIHD KHSLITDVVE IDRHWLKAFR
MVTRNDETGL WDFKNLGDPL PAEPSKPCTT SIPKLNVENF GPTANIINCF VKVLYYMPLH
LDGSRKSRKK GTALVLDKDK GLAVTSRSTV PYDLGDLTIT VADSIQIPAE VVHLHPTQNL
AFIKYDPKLL GDTPIQAAKL KDYYVSQGDP VNFFGFNSKS RVVAAKTSVT DVITMVIPSS
PMPRFRAINF ESITVESNLS TQCGSGVLTD DDGLVVALWL THYGEQTSRG TDVKYHLGLA
SPVVLSTLRR LQSGVNVNPR ILNVEFRAIQ LAQARSLGLP AERIRKIETE SGKKHQLFMI
THVEAGTPRI LTDGDIIISA NGKSITRIRD LQVDDVTEVD MEILREGKVQ TVKVPTFPSD
NCETNRVVIC WGATLQAPHR AVRLQIEDLP SNVFVTNRGR GSPADQYDLG AAQFITAVNG
VTTLNLEDFV REIRKIDDNS YVRVSTSTFD KVPVVLTIKM NKHYFPTIDL VQDAKAENGW
RAVQYDEVGE KKNPSMGFTI DEEVDDNTFD TEGEQQ
