YIFK_SALTY
ID YIFK_SALTY Reviewed; 461 AA.
AC P0A189; P37456; Q9L6Q6;
DT 01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 86.
DE RecName: Full=Probable transport protein YifK;
GN Name=yifK; OrderedLocusNames=STM3930; ORFNames=STMD1.58;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8509342; DOI=10.1128/jb.175.12.3897-3899.1993;
RA Lu C.D., Abdelal A.T.;
RT "The Salmonella typhimurium uracil-sensitive mutation use is in argU and
RT encodes a minor arginine tRNA.";
RL J. Bacteriol. 175:3897-3899(1993).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Probable amino-acid or metabolite transport protein.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. {ECO:0000305}.
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DR EMBL; M95047; AAA92026.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL22779.1; -; Genomic_DNA.
DR EMBL; AF233324; AAF33457.1; -; Genomic_DNA.
DR PIR; S27728; S27728.
DR RefSeq; NP_462820.1; NC_003197.2.
DR RefSeq; WP_000818378.1; NC_003197.2.
DR AlphaFoldDB; P0A189; -.
DR SMR; P0A189; -.
DR STRING; 99287.STM3930; -.
DR PaxDb; P0A189; -.
DR EnsemblBacteria; AAL22779; AAL22779; STM3930.
DR GeneID; 1255456; -.
DR KEGG; stm:STM3930; -.
DR PATRIC; fig|99287.12.peg.4151; -.
DR HOGENOM; CLU_007946_9_3_6; -.
DR OMA; CIAYMNV; -.
DR PhylomeDB; P0A189; -.
DR BioCyc; SENT99287:STM3930-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR004840; Amoino_acid_permease_CS.
DR Pfam; PF00324; AA_permease; 1.
DR PROSITE; PS00218; AMINO_ACID_PERMEASE_1; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Cell inner membrane; Cell membrane; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..461
FT /note="Probable transport protein YifK"
FT /id="PRO_0000054220"
FT TRANSMEM 17..37
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 40..60
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 74..94
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 97..117
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 156..176
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 201..221
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 244..264
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 278..298
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 333..353
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 360..380
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 401..421
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 430..450
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 200
FT /note="K -> E (in Ref. 1; AAA92026)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 461 AA; 50378 MW; 8F4F4356E29AEB90 CRC64;
MAEKKPELQR GLEARHIELI ALGGTIGVGL FMGAASTLKW AGPSVLLAYI IAGLFVFFIM
RSMGEMLFLE PVTGSFAVYA HRYMSPFFGY LTAWSYWFMW MAVGISEITA IGVYVQFWFP
EMAQWIPALI AVGLVALANL AAVRLYGEIE FWFAMIKVTT IIVMIIIGLG VIFFGFGNGG
QAIGFGNLTE HGGFFAGGWK GFLTALCIVV ASYQGVELIG ITAGEAKNPQ VTLRSAVGKV
LWRILIFYVG AIFVIVTIFP WNEIGSNGSP FVLTFAKIGI TAAAGIINFV VLTAALSGCN
SGMYSCGRML YALAKNRQLP AAVAKVSRHG VPVAGVALSI LILLVGSCLN YIIPNPQRVF
VYVYSASVLP GMVPWFVILI SQLRFRRAHK EAIADHPFRS IMFPWANYLT MAFLVCVLIG
MYFNEDTRMS LFVGVIFLLA VTLVYKVFGL NRHGTAHKVG E