YIG7_YEAST
ID YIG7_YEAST Reviewed; 678 AA.
AC P40514; D6VVL7; Q6B2R2;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Uncharacterized protein YIL067C;
GN OrderedLocusNames=YIL067C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169870;
RA Churcher C.M., Bowman S., Badcock K., Bankier A.T., Brown D.,
RA Chillingworth T., Connor R., Devlin K., Gentles S., Hamlin N., Harris D.E.,
RA Horsnell T., Hunt S., Jagels K., Jones M., Lye G., Moule S., Odell C.,
RA Pearson D., Rajandream M.A., Rice P., Rowley N., Skelton J., Smith V.,
RA Walsh S.V., Whitehead S., Barrell B.G.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome IX.";
RL Nature 387:84-87(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [4]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
CC -!- SUBCELLULAR LOCATION: Vacuole membrane {ECO:0000305}; Multi-pass
CC membrane protein {ECO:0000305}.
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DR EMBL; Z38060; CAA86156.1; -; Genomic_DNA.
DR EMBL; AY692668; AAT92687.1; -; Genomic_DNA.
DR EMBL; BK006942; DAA08483.1; -; Genomic_DNA.
DR PIR; S48412; S48412.
DR RefSeq; NP_012197.1; NM_001179417.1.
DR AlphaFoldDB; P40514; -.
DR BioGRID; 34925; 33.
DR IntAct; P40514; 1.
DR MINT; P40514; -.
DR STRING; 4932.YIL067C; -.
DR MaxQB; P40514; -.
DR PaxDb; P40514; -.
DR PRIDE; P40514; -.
DR EnsemblFungi; YIL067C_mRNA; YIL067C; YIL067C.
DR GeneID; 854743; -.
DR KEGG; sce:YIL067C; -.
DR SGD; S000001329; YIL067C.
DR VEuPathDB; FungiDB:YIL067C; -.
DR eggNOG; ENOG502QUEX; Eukaryota.
DR HOGENOM; CLU_011125_2_0_1; -.
DR InParanoid; P40514; -.
DR OMA; YSLWKSG; -.
DR BioCyc; YEAST:G3O-31334-MON; -.
DR PRO; PR:P40514; -.
DR Proteomes; UP000002311; Chromosome IX.
DR RNAct; P40514; protein.
DR GO; GO:0000324; C:fungal-type vacuole; HDA:SGD.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.170.130.20; -; 1.
DR InterPro; IPR004043; LCCL.
DR InterPro; IPR036609; LCCL_sf.
DR Pfam; PF03815; LCCL; 1.
DR SUPFAM; SSF69848; SSF69848; 1.
PE 1: Evidence at protein level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix; Vacuole.
FT CHAIN 1..678
FT /note="Uncharacterized protein YIL067C"
FT /id="PRO_0000202981"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 245..265
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 317..337
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 340..360
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 371..391
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 405..425
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 443..463
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 475..495
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 519..539
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 644
FT /note="A -> T (in Ref. 3; AAT92687)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 678 AA; 75482 MW; B237BB728D029F0C CRC64;
MGVHFDDNAN TTWEATDPGV SSDCDGQHRV TESIQLQNFS NTDMESMLDE EGRENSKSKW
LLLKRKHPIQ KFIERVWNGP VEPSDEPPSF PKRWGWLKKI DDFPQTTFKT KIPSKLIRLL
LLIVYCCFWM RIFYSLIYPY LIKPPYFHPN DGSEKIPILS LSCNSYLNWE GTNNECGLNA
KNCGPLDNKE YMIRCPALCD RGGWTYSAIA VGNRRVKYTG YEIGGGALFS EEDPMVVSYP
YRSDSFPCAS AVHAGVISPF YGGCTKVSMQ GAQNSFPSKK GMYNTGFSVA FNSFFPGSYS
FRDIQGGILS GCYDPRAAVV ALNMLFGLPI FYLYDSIYGY WINTIVGYWT LVLSLDPPLL
TDAHDPASVY ELFSVGFQRL LPLCFVLYVV WKSAVKRTLE NGSPIAKVIL WYPTFWLGIS
NNVTFDRLPV DRLTTTDLKE QAGALTAVGS IAATILTCAV IQAYSLWKSG RFKKYFKIYI
CFIGGLIALG SLPGLNLRIH HYILGSILVP GCATRGSSAY LFQGILVGLI LSGVARWDFA
SIVETDTALL RGEAGASLKP PILDFNDDQN HSLSWHLNAT DPVIDQIGNI DGFSLLLNDV
EVYVGKNETV SIDVLRMENP ALAQMMDDAL DASNGTIDLY LRVARASVRS PTNRGDYTNA
GVLQWPNGMW QKPEPGVS
