ID   YIGG_ECOLI              Reviewed;         126 AA.
AC   P27843; Q2M8C3;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   14-AUG-2001, sequence version 2.
DT   03-AUG-2022, entry version 129.
DE   RecName: Full=Inner membrane protein YigG;
GN   Name=yigG; OrderedLocusNames=b3818, JW5590;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=K12;
RA   Ohmori H.;
RL   Submitted (JAN-1993) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=1379743; DOI=10.1126/science.1379743;
RA   Daniels D.L., Plunkett G. III, Burland V.D., Blattner F.R.;
RT   "Analysis of the Escherichia coli genome: DNA sequence of the region from
RT   84.5 to 86.5 minutes.";
RL   Science 257:771-778(1992).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   SUBCELLULAR LOCATION.
RC   STRAIN=K12 / JM109 / ATCC 53323;
RX   PubMed=11867724; DOI=10.1073/pnas.052018199;
RA   Drew D., Sjoestrand D., Nilsson J., Urbig T., Chin C.-N., de Gier J.-W.,
RA   von Heijne G.;
RT   "Rapid topology mapping of Escherichia coli inner-membrane proteins by
RT   prediction and PhoA/GFP fusion analysis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:2690-2695(2002).
RN   [6]
RP   TOPOLOGY [LARGE SCALE ANALYSIS].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=15919996; DOI=10.1126/science.1109730;
RA   Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT   "Global topology analysis of the Escherichia coli inner membrane
RT   proteome.";
RL   Science 308:1321-1323(2005).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000269|PubMed:11867724}; Multi-pass membrane protein
CC       {ECO:0000269|PubMed:11867724}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA67614.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
CC       Sequence=AAD15040.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; L02122; AAD15040.1; ALT_INIT; Genomic_DNA.
DR   EMBL; M87049; AAA67614.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAC76821.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77483.1; -; Genomic_DNA.
DR   PIR; S30708; S30708.
DR   RefSeq; NP_418262.2; NC_000913.3.
DR   AlphaFoldDB; P27843; -.
DR   BioGRID; 4262615; 4.
DR   STRING; 511145.b3818; -.
DR   PaxDb; P27843; -.
DR   PRIDE; P27843; -.
DR   EnsemblBacteria; AAC76821; AAC76821; b3818.
DR   EnsemblBacteria; BAE77483; BAE77483; BAE77483.
DR   GeneID; 948344; -.
DR   KEGG; ecj:JW5590; -.
DR   KEGG; eco:b3818; -.
DR   PATRIC; fig|511145.12.peg.3934; -.
DR   EchoBASE; EB1433; -.
DR   eggNOG; ENOG5032XE7; Bacteria.
DR   HOGENOM; CLU_1978020_0_0_6; -.
DR   OMA; LVININC; -.
DR   BioCyc; EcoCyc:EG11465-MON; -.
DR   PRO; PR:P27843; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IDA:EcoliWiki.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..126
FT                   /note="Inner membrane protein YigG"
FT                   /id="PRO_0000169657"
FT   TOPO_DOM        1..18
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        19..39
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        40
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        41..61
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        62..67
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        68..88
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        89..100
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..121
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        122..126
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   126 AA;  14408 MW;  4D5DACC960C35B1B CRC64;
     MLRIFIPTSN GKISRRRYIF SFILINFIFA FLIIFFNDGE AGFLVIVSTI VLHYLVINMN
     CQRLRDSGFI YIKTYVFGTL AVYIISIITM IAEDFACSGN GSMIFLICYF STFSMLMLAP
     TDSSKQ