YIHI_SALTY
ID YIHI_SALTY Reviewed; 171 AA.
AC P0A2N8; P37130;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 73.
DE RecName: Full=Der GTPase-activating protein YihI {ECO:0000255|HAMAP-Rule:MF_01058};
GN Name=yihI {ECO:0000255|HAMAP-Rule:MF_01058}; OrderedLocusNames=STM4003;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=LT2;
RX PubMed=8195073; DOI=10.1128/jb.176.11.3196-3203.1994;
RA Xu K., Elliott T.;
RT "Cloning, DNA sequence, and complementation analysis of the Salmonella
RT typhimurium hemN gene encoding a putative oxygen-independent
RT coproporphyrinogen III oxidase.";
RL J. Bacteriol. 176:3196-3203(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: A GTPase-activating protein (GAP) that modifies Der/EngA
CC GTPase function. May play a role in ribosome biogenesis.
CC {ECO:0000255|HAMAP-Rule:MF_01058}.
CC -!- SUBUNIT: Interacts with Der. {ECO:0000255|HAMAP-Rule:MF_01058}.
CC -!- SIMILARITY: Belongs to the YihI family. {ECO:0000255|HAMAP-
CC Rule:MF_01058}.
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DR EMBL; U06779; AAA19691.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL22842.1; -; Genomic_DNA.
DR RefSeq; NP_462883.1; NC_003197.2.
DR RefSeq; WP_000743292.1; NC_003197.2.
DR AlphaFoldDB; P0A2N8; -.
DR SMR; P0A2N8; -.
DR STRING; 99287.STM4003; -.
DR PaxDb; P0A2N8; -.
DR EnsemblBacteria; AAL22842; AAL22842; STM4003.
DR GeneID; 1255529; -.
DR KEGG; stm:STM4003; -.
DR PATRIC; fig|99287.12.peg.4217; -.
DR HOGENOM; CLU_094104_2_0_6; -.
DR OMA; ENNECLN; -.
DR PhylomeDB; P0A2N8; -.
DR BioCyc; SENT99287:STM4003-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR HAMAP; MF_01058; GAP_YihI; 1.
DR InterPro; IPR007336; YihI.
DR Pfam; PF04220; YihI; 1.
PE 3: Inferred from homology;
KW GTPase activation; Reference proteome; Ribosome biogenesis.
FT CHAIN 1..171
FT /note="Der GTPase-activating protein YihI"
FT /id="PRO_0000209592"
FT REGION 1..99
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 145..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..30
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 50..66
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 171 AA; 19213 MW; 285D273E337AC179 CRC64;
MKKPTSAPRS KAFGKQRRKT REELNQEARD RKRLKKHRGH APGSRAAGGN SASGGGNQNQ
QKDPRIGSKT PVPLGVTEKV TQQHKPKSEK PMLSPQAELD LLETDERLDA LLERLEAGET
LSAEDQAWVD AKLDRIDELM QKLGLSYDDD EEDDEEDEKQ EDMMRLLRGG N