YIHI_SHIFL
ID YIHI_SHIFL Reviewed; 169 AA.
AC P0A8H7; P32130;
DT 07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2005, sequence version 1.
DT 25-MAY-2022, entry version 88.
DE RecName: Full=Der GTPase-activating protein YihI {ECO:0000255|HAMAP-Rule:MF_01058};
GN Name=yihI {ECO:0000255|HAMAP-Rule:MF_01058};
GN OrderedLocusNames=SF3936, S3810;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- FUNCTION: A GTPase-activating protein (GAP) that modifies Der/EngA
CC GTPase function. May play a role in ribosome biogenesis.
CC {ECO:0000255|HAMAP-Rule:MF_01058}.
CC -!- SUBUNIT: Interacts with Der. {ECO:0000255|HAMAP-Rule:MF_01058}.
CC -!- SIMILARITY: Belongs to the YihI family. {ECO:0000255|HAMAP-
CC Rule:MF_01058}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE005674; AAN45371.1; -; Genomic_DNA.
DR EMBL; AE014073; AAP18827.1; -; Genomic_DNA.
DR RefSeq; NP_709664.1; NC_004337.2.
DR RefSeq; WP_001295266.1; NZ_WHSI01000064.1.
DR AlphaFoldDB; P0A8H7; -.
DR SMR; P0A8H7; -.
DR STRING; 198214.SF3936; -.
DR PRIDE; P0A8H7; -.
DR EnsemblBacteria; AAN45371; AAN45371; SF3936.
DR EnsemblBacteria; AAP18827; AAP18827; S3810.
DR GeneID; 1027377; -.
DR GeneID; 66672229; -.
DR KEGG; sfl:SF3936; -.
DR KEGG; sfx:S3810; -.
DR PATRIC; fig|198214.7.peg.4638; -.
DR HOGENOM; CLU_094104_2_0_6; -.
DR OrthoDB; 2068666at2; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR HAMAP; MF_01058; GAP_YihI; 1.
DR InterPro; IPR007336; YihI.
DR Pfam; PF04220; YihI; 1.
PE 3: Inferred from homology;
KW GTPase activation; Reference proteome; Ribosome biogenesis.
FT CHAIN 1..169
FT /note="Der GTPase-activating protein YihI"
FT /id="PRO_0000209594"
FT REGION 1..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 144..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..32
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 169 AA; 19059 MW; 31C1DF0C07AD9D07 CRC64;
MKPSSSNSRS KGHAKARRKT REELDQEARD RKRQKKRRGH APGSRAAGGN TTSGSKGQNA
PKDPRIGSKT PIPLGVTEKV TKQHKPKSEK PMLSPQAELE LLETDERLDA LLERLEAGET
LSAEEQSWVD AKLDRIDELM QKLGLSYDDD EEEEEDEKQE DMMRLLRGN
