ID   YIHI_VIBC3              Reviewed;         182 AA.
AC   A5F4H7; C3M2D0;
DT   26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Der GTPase-activating protein YihI {ECO:0000255|HAMAP-Rule:MF_01058};
GN   Name=yihI {ECO:0000255|HAMAP-Rule:MF_01058};
GN   OrderedLocusNames=VC0395_A2404, VC395_0066;
OS   Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 /
OS   O395).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=345073;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RA   Heidelberg J.;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39541 / Classical Ogawa 395 / O395;
RX   PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA   Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA   Wang W., Wang J., Qian W., Li D., Wang L.;
RT   "A recalibrated molecular clock and independent origins for the cholera
RT   pandemic clones.";
RL   PLoS ONE 3:E4053-E4053(2008).
CC   -!- FUNCTION: A GTPase-activating protein (GAP) that modifies Der/EngA
CC       GTPase function. May play a role in ribosome biogenesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01058}.
CC   -!- SUBUNIT: Interacts with Der. {ECO:0000255|HAMAP-Rule:MF_01058}.
CC   -!- SIMILARITY: Belongs to the YihI family. {ECO:0000255|HAMAP-
CC       Rule:MF_01058}.
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DR   EMBL; CP000627; ABQ20042.1; -; Genomic_DNA.
DR   EMBL; CP001235; ACP08094.1; -; Genomic_DNA.
DR   RefSeq; WP_000091428.1; NZ_JAACZH010000014.1.
DR   AlphaFoldDB; A5F4H7; -.
DR   SMR; A5F4H7; -.
DR   STRING; 345073.VC395_0066; -.
DR   EnsemblBacteria; ABQ20042; ABQ20042; VC0395_A2404.
DR   KEGG; vco:VC0395_A2404; -.
DR   KEGG; vcr:VC395_0066; -.
DR   PATRIC; fig|345073.21.peg.63; -.
DR   eggNOG; COG3078; Bacteria.
DR   HOGENOM; CLU_094104_1_0_6; -.
DR   OMA; ENNECLN; -.
DR   Proteomes; UP000000249; Chromosome 2.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   HAMAP; MF_01058; GAP_YihI; 1.
DR   InterPro; IPR007336; YihI.
DR   Pfam; PF04220; YihI; 1.
PE   3: Inferred from homology;
KW   GTPase activation; Ribosome biogenesis.
FT   CHAIN           1..182
FT                   /note="Der GTPase-activating protein YihI"
FT                   /id="PRO_1000073000"
FT   REGION          1..79
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          143..182
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..22
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        156..182
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   182 AA;  20751 MW;  236EDBC201C143A4 CRC64;
     MSRSKKSRKP GTNSNDQLVV VRTRSESELE SRLRKKLKKR KGLKSGSRHS EGSESQVRQA
     AQKRDPRLGS KKPIPLIVAE PKKLNKQERK LAAEQELAML EKDAQLNVLL DRLDNGEKLG
     IGLQKYVDEK LDRIEVLMEQ LGLLDDEPEP APAPQSKPTK KRKTEDDLLS EFEQLDVDKY
     QD