ID   YIHI_VIBCH              Reviewed;         182 AA.
AC   Q9KVM7;
DT   30-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Der GTPase-activating protein YihI {ECO:0000255|HAMAP-Rule:MF_01058};
GN   Name=yihI {ECO:0000255|HAMAP-Rule:MF_01058}; OrderedLocusNames=VC_0114;
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC   Vibrio.
OX   NCBI_TaxID=243277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961;
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A., Gill S.R.,
RA   Nelson K.E., Read T.D., Tettelin H., Richardson D.L., Ermolaeva M.D.,
RA   Vamathevan J.J., Bass S., Qin H., Dragoi I., Sellers P., McDonald L.A.,
RA   Utterback T.R., Fleischmann R.D., Nierman W.C., White O., Salzberg S.L.,
RA   Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C., Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- FUNCTION: A GTPase-activating protein (GAP) that modifies Der/EngA
CC       GTPase function. May play a role in ribosome biogenesis.
CC       {ECO:0000255|HAMAP-Rule:MF_01058}.
CC   -!- SUBUNIT: Interacts with Der. {ECO:0000255|HAMAP-Rule:MF_01058}.
CC   -!- SIMILARITY: Belongs to the YihI family. {ECO:0000255|HAMAP-
CC       Rule:MF_01058}.
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DR   EMBL; AE003852; AAF93292.1; -; Genomic_DNA.
DR   PIR; H82361; H82361.
DR   RefSeq; NP_229773.1; NC_002505.1.
DR   RefSeq; WP_000091428.1; NZ_LT906614.1.
DR   AlphaFoldDB; Q9KVM7; -.
DR   SMR; Q9KVM7; -.
DR   STRING; 243277.VC_0114; -.
DR   DNASU; 2614424; -.
DR   EnsemblBacteria; AAF93292; AAF93292; VC_0114.
DR   KEGG; vch:VC_0114; -.
DR   PATRIC; fig|243277.26.peg.105; -.
DR   eggNOG; COG3078; Bacteria.
DR   HOGENOM; CLU_094104_1_0_6; -.
DR   OMA; ENNECLN; -.
DR   BioCyc; VCHO:VC0114-MON; -.
DR   Proteomes; UP000000584; Chromosome 1.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   HAMAP; MF_01058; GAP_YihI; 1.
DR   InterPro; IPR007336; YihI.
DR   Pfam; PF04220; YihI; 1.
PE   3: Inferred from homology;
KW   GTPase activation; Reference proteome; Ribosome biogenesis.
FT   CHAIN           1..182
FT                   /note="Der GTPase-activating protein YihI"
FT                   /id="PRO_0000209595"
FT   REGION          1..79
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          143..182
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..22
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        156..182
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   182 AA;  20751 MW;  236EDBC201C143A4 CRC64;
     MSRSKKSRKP GTNSNDQLVV VRTRSESELE SRLRKKLKKR KGLKSGSRHS EGSESQVRQA
     AQKRDPRLGS KKPIPLIVAE PKKLNKQERK LAAEQELAML EKDAQLNVLL DRLDNGEKLG
     IGLQKYVDEK LDRIEVLMEQ LGLLDDEPEP APAPQSKPTK KRKTEDDLLS EFEQLDVDKY
     QD