YIHI_YERPA
ID YIHI_YERPA Reviewed; 188 AA.
AC Q1C238;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2006, sequence version 1.
DT 25-MAY-2022, entry version 63.
DE RecName: Full=Der GTPase-activating protein YihI {ECO:0000255|HAMAP-Rule:MF_01058};
GN Name=yihI {ECO:0000255|HAMAP-Rule:MF_01058}; OrderedLocusNames=YPA_3522;
OS Yersinia pestis bv. Antiqua (strain Antiqua).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Yersinia.
OX NCBI_TaxID=360102;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Antiqua;
RX PubMed=16740952; DOI=10.1128/jb.00124-06;
RA Chain P.S.G., Hu P., Malfatti S.A., Radnedge L., Larimer F., Vergez L.M.,
RA Worsham P., Chu M.C., Andersen G.L.;
RT "Complete genome sequence of Yersinia pestis strains Antiqua and Nepal516:
RT evidence of gene reduction in an emerging pathogen.";
RL J. Bacteriol. 188:4453-4463(2006).
CC -!- FUNCTION: A GTPase-activating protein (GAP) that modifies Der/EngA
CC GTPase function. May play a role in ribosome biogenesis.
CC {ECO:0000255|HAMAP-Rule:MF_01058}.
CC -!- SUBUNIT: Interacts with Der. {ECO:0000255|HAMAP-Rule:MF_01058}.
CC -!- SIMILARITY: Belongs to the YihI family. {ECO:0000255|HAMAP-
CC Rule:MF_01058}.
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DR EMBL; CP000308; ABG15484.1; -; Genomic_DNA.
DR RefSeq; WP_002213158.1; NZ_CP009906.1.
DR AlphaFoldDB; Q1C238; -.
DR SMR; Q1C238; -.
DR EnsemblBacteria; ABG15484; ABG15484; YPA_3522.
DR GeneID; 66843584; -.
DR KEGG; ypa:YPA_3522; -.
DR OMA; ENNECLN; -.
DR Proteomes; UP000001971; Chromosome.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR HAMAP; MF_01058; GAP_YihI; 1.
DR InterPro; IPR007336; YihI.
DR Pfam; PF04220; YihI; 1.
PE 3: Inferred from homology;
KW GTPase activation; Ribosome biogenesis.
FT CHAIN 1..188
FT /note="Der GTPase-activating protein YihI"
FT /id="PRO_1000064437"
FT REGION 1..80
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 162..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..40
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 171..188
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 188 AA; 21348 MW; F65588CCC12CBD1F CRC64;
MKQPNKAPRA NIAAPKGTAT PKRRRKTRDE LDAEARDRKR QKKHSGNRSG ARTNVEGSNK
KGHSQTQEKD PRVGSKVPVP LVIESQVKAK SMPKPVEKNV VKPRLTPEEE LAKLENDERL
DALLDRLDND EVLNKEDQAY VDLTLDRIDA LMEQLGIELG DDEDDVEREE KQEDILQLLK
RGNPKDTF