ID   YIHO_ECOLI              Reviewed;         467 AA.
AC   P32136; P76774; Q2M8H3; Q6BEY1;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 4.
DT   03-AUG-2022, entry version 149.
DE   RecName: Full=Putative sulfoquinovose importer;
GN   Name=yihO; OrderedLocusNames=b3876, JW5852;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=8346018; DOI=10.1093/nar/21.15.3391;
RA   Plunkett G. III, Burland V., Daniels D.L., Blattner F.R.;
RT   "Analysis of the Escherichia coli genome. III. DNA sequence of the region
RT   from 87.2 to 89.2 minutes.";
RL   Nucleic Acids Res. 21:3391-3398(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND SEQUENCE REVISION.
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   SEQUENCE REVISION.
RX   PubMed=16397293; DOI=10.1093/nar/gkj405;
RA   Riley M., Abe T., Arnaud M.B., Berlyn M.K.B., Blattner F.R.,
RA   Chaudhuri R.R., Glasner J.D., Horiuchi T., Keseler I.M., Kosuge T.,
RA   Mori H., Perna N.T., Plunkett G. III, Rudd K.E., Serres M.H., Thomas G.H.,
RA   Thomson N.R., Wishart D., Wanner B.L.;
RT   "Escherichia coli K-12: a cooperatively developed annotation snapshot
RT   -- 2005.";
RL   Nucleic Acids Res. 34:1-9(2006).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
RN   [5]
RP   FUNCTION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=K12;
RX   PubMed=24463506; DOI=10.1038/nature12947;
RA   Denger K., Weiss M., Felux A.K., Schneider A., Mayer C., Spiteller D.,
RA   Huhn T., Cook A.M., Schleheck D.;
RT   "Sulphoglycolysis in Escherichia coli K-12 closes a gap in the
RT   biogeochemical sulphur cycle.";
RL   Nature 507:114-117(2014).
CC   -!- FUNCTION: Could be involved in sulfoquinovose import.
CC       {ECO:0000269|PubMed:24463506}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- DISRUPTION PHENOTYPE: Mutant fails to grow on sulfoquinovose as a sole
CC       carbon source. {ECO:0000269|PubMed:24463506}.
CC   -!- SIMILARITY: Belongs to the sodium:galactoside symporter (TC 2.A.2)
CC       family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB03009.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; L19201; AAB03009.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; U00096; AAT48233.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77433.1; -; Genomic_DNA.
DR   RefSeq; WP_001295267.1; NZ_SSZK01000026.1.
DR   RefSeq; YP_026275.1; NC_000913.3.
DR   AlphaFoldDB; P32136; -.
DR   SMR; P32136; -.
DR   BioGRID; 4262636; 11.
DR   STRING; 511145.b3876; -.
DR   TCDB; 2.A.2.3.15; the glycoside-pentoside-hexuronide (gph):cation symporter family.
DR   PaxDb; P32136; -.
DR   PRIDE; P32136; -.
DR   EnsemblBacteria; AAT48233; AAT48233; b3876.
DR   EnsemblBacteria; BAE77433; BAE77433; BAE77433.
DR   GeneID; 948377; -.
DR   KEGG; ecj:JW5852; -.
DR   KEGG; eco:b3876; -.
DR   PATRIC; fig|1411691.4.peg.2835; -.
DR   EchoBASE; EB1787; -.
DR   eggNOG; COG2211; Bacteria.
DR   HOGENOM; CLU_027408_0_1_6; -.
DR   InParanoid; P32136; -.
DR   OMA; DIIDYGE; -.
DR   PhylomeDB; P32136; -.
DR   BioCyc; EcoCyc:YIHO-MON; -.
DR   BioCyc; MetaCyc:YIHO-MON; -.
DR   PRO; PR:P32136; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR   GO; GO:1901682; F:sulfur compound transmembrane transporter activity; IMP:EcoCyc.
DR   GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR   GO; GO:0008643; P:carbohydrate transport; IEA:InterPro.
DR   GO; GO:0071702; P:organic substance transport; IBA:GO_Central.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   GO; GO:0072348; P:sulfur compound transport; IMP:EcoCyc.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR039672; MFS_2.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   InterPro; IPR001927; Na/Gal_symport.
DR   InterPro; IPR018043; Na/Gal_symport_CS.
DR   PANTHER; PTHR11328; PTHR11328; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   TIGRFAMs; TIGR00792; gph; 1.
DR   PROSITE; PS00872; NA_GALACTOSIDE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome; Symport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..467
FT                   /note="Putative sulfoquinovose importer"
FT                   /id="PRO_0000170767"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        88..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        160..180
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        238..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        275..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        303..323
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        325..345
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        379..399
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        414..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   467 AA;  51574 MW;  567044C9C4689619 CRC64;
     MSDHNPLTLK LNLREKIAYG MGDVGSNLML CIGTLYLLKF YTDELGMPAY YGGIIFLVAK
     FFTAFTDMLT GFLLDSRKNI GPKGKFRPFI LYAAVPAALI ATLQFIATTF CLPVKTTIAT
     ALFMMFGLSY SLMNCSYGAM IPAITKNPNE RAQLAAYRQG GATIGLLICT VAFIPLQSLF
     SDSTVGYACA ALMFSIGGFI FMMLCYRGVK EHYVDTTPTG HKASILKSFC AIFRNPPLLV
     LCIANLCTLA AFNIKLAIQV YYTQYVLNDI NLLSWMGFFS MGCILIGVLL VPLTVKCFGK
     KQVYLAGMVL WAVGDILNYF WGSNSFTFVM FSCVAFFGTA FVNSLNWALV PDTVDYGEWK
     TGIRAEGSVY TGYTFFRKIS AALAGFLPGI MLTQIGYVPN IAQSDATLQG LRQLIFIWPC
     ALAIIAALTM GFFYTLNEKR FALIIEEINQ RKNKEMATEE KTASVTL