YIHY_ECOLI
ID YIHY_ECOLI Reviewed; 290 AA.
AC P0A8K8; P32146; Q2M8I3;
DT 07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2005, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=UPF0761 membrane protein YihY;
GN Name=yihY; OrderedLocusNames=b3886, JW3857; ORFNames=b2268;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=B, and K12 / CA265;
RX PubMed=8955422; DOI=10.1128/jb.178.24.7329-7332.1996;
RA Callahan C., Deutscher M.P.;
RT "Identification and characterization of the Escherichia coli rbn gene
RT encoding the tRNA processing enzyme RNase BN.";
RL J. Bacteriol. 178:7329-7332(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=8346018; DOI=10.1093/nar/21.15.3391;
RA Plunkett G. III, Burland V., Daniels D.L., Blattner F.R.;
RT "Analysis of the Escherichia coli genome. III. DNA sequence of the region
RT from 87.2 to 89.2 minutes.";
RL Nucleic Acids Res. 21:3391-3398(1993).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP SHOWS THAT IT IS NOT RNASE BN.
RX PubMed=15764599; DOI=10.1074/jbc.c500098200;
RA Ezraty B., Dahlgren B., Deutscher M.P.;
RT "The RNase Z homologue encoded by Escherichia coli elaC gene is RNase BN.";
RL J. Biol. Chem. 280:16542-16545(2005).
RN [6]
RP SUBCELLULAR LOCATION, AND TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000269|PubMed:15919996}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:15919996}.
CC -!- SIMILARITY: Belongs to the UPF0761 family. {ECO:0000305}.
CC -!- CAUTION: Was originally (PubMed:8955422) thought to be the tRNA-
CC processing ribonuclease BN (rbn). This was later proven not to be the
CC case (PubMed:15764599). {ECO:0000305|PubMed:15764599,
CC ECO:0000305|PubMed:8955422}.
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DR EMBL; L19201; AAB03019.1; -; Genomic_DNA.
DR EMBL; U00096; AAD13448.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE77423.1; -; Genomic_DNA.
DR PIR; S40830; S40830.
DR RefSeq; NP_418322.1; NC_000913.3.
DR RefSeq; WP_000920762.1; NZ_STEB01000017.1.
DR AlphaFoldDB; P0A8K8; -.
DR BioGRID; 4260958; 25.
DR STRING; 511145.b3886; -.
DR TCDB; 9.B.126.2.1; the putative lipid iv exporter (yhjd) family.
DR jPOST; P0A8K8; -.
DR PaxDb; P0A8K8; -.
DR PRIDE; P0A8K8; -.
DR DNASU; 948379; -.
DR EnsemblBacteria; AAD13448; AAD13448; b3886.
DR EnsemblBacteria; BAE77423; BAE77423; BAE77423.
DR GeneID; 66672208; -.
DR GeneID; 948379; -.
DR KEGG; ecj:JW3857; -.
DR KEGG; eco:b3886; -.
DR PATRIC; fig|1411691.4.peg.2825; -.
DR EchoBASE; EB1797; -.
DR eggNOG; COG1295; Bacteria.
DR HOGENOM; CLU_032288_0_0_6; -.
DR OMA; KQPKFRW; -.
DR PhylomeDB; P0A8K8; -.
DR BioCyc; EcoCyc:EG11851-MON; -.
DR PRO; PR:P0A8K8; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR HAMAP; MF_00672; UPF0761; 1.
DR InterPro; IPR023679; UPF0761_bac.
DR InterPro; IPR017039; Virul_fac_BrkB.
DR PANTHER; PTHR30213; PTHR30213; 1.
DR Pfam; PF03631; Virul_fac_BrkB; 1.
DR PIRSF; PIRSF035875; RNase_BN; 1.
DR TIGRFAMs; TIGR00765; yihY_not_rbn; 1.
PE 1: Evidence at protein level;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..290
FT /note="UPF0761 membrane protein YihY"
FT /id="PRO_0000200981"
FT TOPO_DOM 1..38
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 39..61
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 62..100
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 101..120
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 121..140
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 141..163
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 164..182
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 183..205
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 206..211
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 212..234
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 235..243
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 244..266
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 267..290
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 290 AA; 32839 MW; E027DAB37200CA93 CRC64;
MLKTIQDKAR HRTRPLWAWL KLLWQRIDED NMTTLAGNLA YVSLLSLVPL VAVVFALFAA
FPMFSDVSIQ LRHFIFANFL PATGDVIQRY IEQFVANSNK MTAVGACGLI VTALLLMYSI
DSALNTIWRS KRARPKIYSF AVYWMILTLG PLLAGASLAI SSYLLSLRWA SDLNTVIDNV
LRIFPLLLSW ISFWLLYSIV PTIRVPNRDA IVGAFVAALL FEAGKKGFAL YITMFPSYQL
IYGVLAVIPI LFVWVYWTWC IVLLGAEITV TLGEYRKLKQ AAEQEEDDEP
