ID   YIHY_SHIFL              Reviewed;         290 AA.
AC   Q83MJ2;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=UPF0761 membrane protein YihY {ECO:0000255|HAMAP-Rule:MF_00672};
GN   Name=yihY {ECO:0000255|HAMAP-Rule:MF_00672};
GN   OrderedLocusNames=SF3958, S3788;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00672}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00672}.
CC   -!- SIMILARITY: Belongs to the UPF0761 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00672}.
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DR   EMBL; AE005674; AAN45393.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP18807.1; -; Genomic_DNA.
DR   RefSeq; NP_709686.1; NC_004337.2.
DR   AlphaFoldDB; Q83MJ2; -.
DR   STRING; 198214.SF3958; -.
DR   EnsemblBacteria; AAN45393; AAN45393; SF3958.
DR   EnsemblBacteria; AAP18807; AAP18807; S3788.
DR   GeneID; 1026582; -.
DR   KEGG; sfl:SF3958; -.
DR   KEGG; sfx:S3788; -.
DR   PATRIC; fig|198214.7.peg.4663; -.
DR   HOGENOM; CLU_032288_0_0_6; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00672; UPF0761; 1.
DR   InterPro; IPR023679; UPF0761_bac.
DR   InterPro; IPR017039; Virul_fac_BrkB.
DR   PANTHER; PTHR30213; PTHR30213; 1.
DR   Pfam; PF03631; Virul_fac_BrkB; 1.
DR   PIRSF; PIRSF035875; RNase_BN; 1.
DR   TIGRFAMs; TIGR00765; yihY_not_rbn; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..290
FT                   /note="UPF0761 membrane protein YihY"
FT                   /id="PRO_0000200997"
FT   TOPO_DOM        1..43
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        44..64
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TOPO_DOM        65..103
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TOPO_DOM        125..139
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        140..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TOPO_DOM        161..182
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        183..203
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TOPO_DOM        204..209
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        210..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TOPO_DOM        231..243
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00672"
FT   TOPO_DOM        265..290
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        166
FT                   /note="P -> S (in Ref. 2; AAP18807)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   290 AA;  32849 MW;  E027D86373D0C993 CRC64;
     MLKTIQDKAR HRTRPLWAWL KLLWQRIDED NMTTLAGNLA YVSLLSLVPL VAVVFALFAA
     FPMFSDVSIQ LRHFIFANFL PATGDVIQRY IEQFVANSNK MTAVGACGLI VTALLLMYSI
     DSALNTIWRS KRARPKIYSF AVYWMILTLG PLLAGASLAI SSYLLPLRWA SDLNTVIDNV
     LRIFPLLLSW ISFWLLYSIV PTIRVPNRDA IVGAFVAALL FEAGKKGFAL YITMFPSYQL
     IYGVLAVIPI LFVWVYWTWC IVLLGAEITV TLGEYRKLKQ AAEQEEDDEP